Parallel homochiral and anti-parallel heterochiral hydrogen-bonding interfaces in multi-helical abiotic foldamers
dc.rights.license | open | en_US |
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hal.structure.identifier | Chimie et Biologie des Membranes et des Nanoobjets [CBMN] | |
dc.contributor.author | MAZZIER, Daniela | |
hal.structure.identifier | Chimie et Biologie des Membranes et des Nanoobjets [CBMN] | |
dc.contributor.author | DE, Soumen | |
dc.contributor.author | WICHER, Barbara | |
hal.structure.identifier | Chimie et Biologie des Membranes et des Nanoobjets [CBMN] | |
dc.contributor.author | MAURIZOT, Victor | |
hal.structure.identifier | Chimie et Biologie des Membranes et des Nanoobjets [CBMN] | |
dc.contributor.author | HUC, Ivan | |
dc.date.accessioned | 2020-05-11T13:08:30Z | |
dc.date.available | 2020-05-11T13:08:30Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 1433-7851 | en_US |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/7517 | |
dc.description.abstractEn | A hydrogen-bonding interface between helical aromatic oligoamide foldamers has been designed to promote the folding of a helix-turn-helix motif with a head-to-tail arrangement of two helices of opposite handedness. This design complements an earlier helix-turn-helix motif with a head-to-head arrangement of two helices of identical handedness interface. The two motifs were shown to have comparable stability and were combined in a unimolecular tetra-helix fold constituting the largest abiotic tertiary structure to date. | |
dc.language.iso | EN | en_US |
dc.subject.en | foldamers | |
dc.subject.en | helix bundles | |
dc.subject.en | molecular design | |
dc.subject.en | structure elucidation | |
dc.subject.en | tertiary structures | |
dc.title.en | Parallel homochiral and anti-parallel heterochiral hydrogen-bonding interfaces in multi-helical abiotic foldamers | |
dc.title.alternative | Angew.Chem.Int. | en_US |
dc.type | Article de revue | en_US |
dc.identifier.doi | 10.1002/anie.201912805 | en_US |
dc.subject.hal | Chimie/Matériaux | en_US |
bordeaux.journal | Angewandte Chemie (International ed. in English) | en_US |
bordeaux.page | 1606-1610 | en_US |
bordeaux.volume | 59 | en_US |
bordeaux.hal.laboratories | Institut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN) - UMR 5248 | en_US |
bordeaux.issue | 4 | en_US |
bordeaux.institution | Bordeaux INP | en_US |
bordeaux.institution | Université de Bordeaux | en_US |
bordeaux.peerReviewed | oui | en_US |
bordeaux.inpress | non | en_US |
bordeaux.identifier.funderID | FP7 Ideas: European Research Council | en_US |
hal.identifier | hal-02569715 | |
hal.version | 1 | |
hal.date.transferred | 2020-05-11T13:08:40Z | |
hal.export | true | |
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