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Parallel homochiral and anti-parallel heterochiral hydrogen-bonding interfaces in multi-helical abiotic foldamers

dc.rights.licenseopenen_US
dc.relation.isnodouble8787c50e-c20a-4284-95e8-7807da1c97d8*
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hal.structure.identifierChimie et Biologie des Membranes et des Nanoobjets [CBMN]
dc.contributor.authorMAZZIER, Daniela
hal.structure.identifierChimie et Biologie des Membranes et des Nanoobjets [CBMN]
dc.contributor.authorDE, Soumen
dc.contributor.authorWICHER, Barbara
hal.structure.identifierChimie et Biologie des Membranes et des Nanoobjets [CBMN]
dc.contributor.authorMAURIZOT, Victor
hal.structure.identifierChimie et Biologie des Membranes et des Nanoobjets [CBMN]
dc.contributor.authorHUC, Ivan
dc.date.accessioned2020-05-11T13:08:30Z
dc.date.available2020-05-11T13:08:30Z
dc.date.issued2019
dc.identifier.issn1433-7851en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/7517
dc.description.abstractEnA hydrogen-bonding interface between helical aromatic oligoamide foldamers has been designed to promote the folding of a helix-turn-helix motif with a head-to-tail arrangement of two helices of opposite handedness. This design complements an earlier helix-turn-helix motif with a head-to-head arrangement of two helices of identical handedness interface. The two motifs were shown to have comparable stability and were combined in a unimolecular tetra-helix fold constituting the largest abiotic tertiary structure to date.
dc.language.isoENen_US
dc.subject.enfoldamers
dc.subject.enhelix bundles
dc.subject.enmolecular design
dc.subject.enstructure elucidation
dc.subject.entertiary structures
dc.title.enParallel homochiral and anti-parallel heterochiral hydrogen-bonding interfaces in multi-helical abiotic foldamers
dc.title.alternativeAngew.Chem.Int.en_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1002/anie.201912805en_US
dc.subject.halChimie/Matériauxen_US
bordeaux.journalAngewandte Chemie (International ed. in English)en_US
bordeaux.page1606-1610en_US
bordeaux.volume59en_US
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN) - UMR 5248en_US
bordeaux.issue4en_US
bordeaux.institutionBordeaux INPen_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDFP7 Ideas: European Research Councilen_US
hal.identifierhal-02569715
hal.version1
hal.date.transferred2020-05-11T13:08:40Z
hal.exporttrue
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