Coiled-coil oligomerization controls localization of the plasma membrane REMORINs.
| dc.rights.license | open | en_US |
| dc.contributor.author | MARTINEZ, Denis | |
| dc.contributor.author | LEGRAND, Anthony | |
| dc.contributor.author | GRONNIER, Julien | |
| dc.contributor.author | DECOSSAS, Marion | |
| dc.contributor.author | GOUGUET, Paul | |
| dc.contributor.author | LAMBERT, Olivier | |
| dc.contributor.author | BERBON, Melanie | |
| dc.contributor.author | VERRON, Loris | |
| dc.contributor.author | GRÉLARD, Axelle | |
| dc.contributor.author | GERMAIN, Veronique | |
| dc.contributor.author | LOQUET, Antoine | |
| dc.contributor.author | MONGRAND, Sébastien | |
| dc.contributor.author | HABENSTEIN, Birgit | |
| dc.date.accessioned | 2019 | |
| dc.date.available | 2019 | |
| dc.date.issued | 2019 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/3805 | |
| dc.description.abstractEn | REMORINs are nanodomain-organized proteins located in the plasma membrane and involved in cellular re-sponses in plants. The dynamic assembly of the membrane nanodomains represents an essential tool of theversatile membrane barriers to control and modulate cellular functions. Nevertheless, the assembly mechanismsand protein organization strategies of nanodomains are poorly understood and many structural aspects aredifficult to visualize. Using an ensemble of biophysical approaches, including solid-state nuclear magnetic re-sonance, cryo-electron microscopy andin vivoconfocal imaging, we providefirst insights on the role and thestructural mechanisms of REMORIN trimerization. Our results suggest that the formation of REMORIN coiled-coil trimers is essential for membrane recruitment and promotes REMORIN assemblyin vitrointo longfilamentsby trimer-trimer interactions that might participate in nanoclustering into membrane domainsin vivo. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | REMORIN | |
| dc.subject.en | Nanodomain | |
| dc.subject.en | Membrane protein | |
| dc.subject.en | Solid-state NMR | |
| dc.subject.en | Protein filament | |
| dc.title.en | Coiled-coil oligomerization controls localization of the plasma membrane REMORINs. | |
| dc.type | Article de revue | en_US |
| dc.subject.hal | Informatique [cs]/Ingénierie assistée par ordinateur | en_US |
| dc.subject.hal | Informatique [cs]/Interface homme-machine [cs.HC] | en_US |
| dc.subject.hal | Sciences de l'ingénieur [physics]/Mécanique [physics.med-ph]/Génie mécanique [physics.class-ph] | en_US |
| bordeaux.journal | Journal of Structural Biology | en_US |
| bordeaux.page | 12-19 | en_US |
| bordeaux.volume | 206 | en_US |
| bordeaux.hal.laboratories | Institut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN) - UMR 5248 | |
| bordeaux.issue | 1 | en_US |
| bordeaux.institution | Bordeaux INP | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-03181424 | |
| hal.version | 1 | |
| hal.date.transferred | 2021-03-25T14:48:34Z | |
| hal.export | true | |
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