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dc.rights.licenseembargoen_US
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
hal.structure.identifierTeam 3 LCPO : Polymer Self-Assembly & Life Sciences
dc.contributor.authorROSSELIN, Marie
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
hal.structure.identifierTeam 3 LCPO : Polymer Self-Assembly & Life Sciences
dc.contributor.authorCHINOY, Zoeisha S.
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
hal.structure.identifierTeam 3 LCPO : Polymer Self-Assembly & Life Sciences
dc.contributor.authorBRAVO-ANAYA, Lourdes Mónica
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
hal.structure.identifierTeam 3 LCPO : Polymer Self-Assembly & Life Sciences
dc.contributor.authorLECOMMANDOUX, Sebastien
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
hal.structure.identifierTeam 3 LCPO : Polymer Self-Assembly & Life Sciences
dc.contributor.authorGARANGER, Elisabeth
IDREF: 089451740
dc.date.accessioned2021-01-06T16:54:40Z
dc.date.available2021-01-06T16:54:40Z
dc.date.issued2020-12-17
dc.identifier.issn2161-1653en_US
dc.identifier.urioai:crossref.org:10.1021/acsmacrolett.0c00775
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/23718
dc.description.abstractEnA library of synthetic elastin-like glycopolypeptides were synthesized and screened by microscale thermophoresis to identify key structural parameters affecting lectin binding efficacy. While polypeptide backbone size and glycovalency were found to have little influence, the presence of a linker at the anomeric position of galactose and the absence of positive charge on the polypeptide residue holding the sugar unit were found to be critical for the binding to RCA120.
dc.description.sponsorshipDéveloppement de squelettes polypeptidiques recombinants pour la synthèse de glycoconjugués multivalents parfaitement définis - ANR-15-CE07-0002en_US
dc.language.isoENen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.sourcecrossref
dc.subject.enElastin-like polypeptides (ELPs)
dc.subject.ensaccharides
dc.subject.englycoconjugates
dc.subject.enchemoselective modifications
dc.subject.enmacromolecular click chemistry
dc.subject.enlectins
dc.title.enMultivalent Elastin-Like Glycopolypeptides: Subtle Chemical Structure Modifications with High Impact on Lectin Binding Affinity
dc.typeArticle de revueen_US
dc.identifier.doi10.1021/acsmacrolett.0c00775en_US
dc.subject.halChimie/Polymèresen_US
dc.subject.halSciences du Vivant [q-bio]/Biotechnologiesen_US
bordeaux.journalACS Macro Lettersen_US
bordeaux.page65-70en_US
bordeaux.volume10en_US
bordeaux.hal.laboratoriesLaboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629en_US
bordeaux.institutionBordeaux INPen_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDAgence Nationale de la Rechercheen_US
bordeaux.import.sourcedissemin
hal.identifierhal-03100778
hal.version1
hal.date.transferred2021-01-06T16:54:45Z
hal.exporttrue
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