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dc.rights.licenseopenen_US
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
hal.structure.identifierTeam 3 LCPO : Polymer Self-Assembly & Life Sciences
dc.contributor.authorLEVÊQUE, Manon
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
hal.structure.identifierTeam 3 LCPO : Polymer Self-Assembly & Life Sciences
dc.contributor.authorLECOMMANDOUX, Sébastien
hal.structure.identifierLaboratoire de Chimie des Polymères Organiques [LCPO]
hal.structure.identifierTeam 3 LCPO : Polymer Self-Assembly & Life Sciences
dc.contributor.authorGARANGER, Elisabeth
IDREF: 089451740
dc.date.accessioned2024-08-19T14:36:44Z
dc.date.available2024-08-19T14:36:44Z
dc.date.issued2024-05-13
dc.identifier.issn1526-4602en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/201176
dc.description.abstractEnStabilization against the dilution-dependent disassembly of self-assembled nanoparticles is a requirement for application. Herein, we propose a simple and biocompatible cross-linking reaction for the stabilization of a series of nanoparticles formed by the self-assembly of amphiphilic HA--ELP block copolymers, through the alkylation of methionine residues from the ELP block with diglycidyl ether compounds. The core-cross-linked nanoparticles retain their colloidal properties, with a spherical core-shell morphology, while maintaining thermoresponsive behavior. As such, instead of a reversible disassembly when non-cross-linked, a reversible swelling of nanoparticles' core and increase of hydrodynamic diameter are observed with lowering of the temperature.
dc.language.isoENen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subject.enNanoparticles
dc.subject.enCross-Linking Reagents
dc.subject.enTemperature
dc.subject.enPolymers
dc.subject.enElastin
dc.subject.enParticle Size
dc.title.enThermoresponsive Core-cross-linked Nanoparticles from HA--ELP Diblock Copolymers.
dc.title.alternativeBiomacromoleculesen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1021/acs.biomac.4c00137en_US
dc.subject.halChimie/Polymèresen_US
dc.identifier.pubmed38689515en_US
bordeaux.journalBiomacromoleculesen_US
bordeaux.page3011-3017en_US
bordeaux.volume25en_US
bordeaux.hal.laboratoriesLaboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629en_US
bordeaux.issue5en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionBordeaux INPen_US
bordeaux.institutionCNRSen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcepubmed
hal.identifierhal-04673008
hal.version1
hal.date.transferred2024-08-19T14:36:46Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
workflow.import.sourcepubmed
dc.rights.ccCC BY-NC-SAen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Biomacromolecules&rft.date=2024-05-13&rft.volume=25&rft.issue=5&rft.spage=3011-3017&rft.epage=3011-3017&rft.eissn=1526-4602&rft.issn=1526-4602&rft.au=LEV%C3%8AQUE,%20Manon&LECOMMANDOUX,%20S%C3%A9bastien&GARANGER,%20Elisabeth&rft.genre=article


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