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Stimulation cognitive et fonctions exécutives dans la maladie d’Alzheimer : une étude pilote

dc.rights.licenseopenen_US
hal.structure.identifierLaboratoire de psychologie [LabPsy]
dc.contributor.authorLAPRE, Emiline
hal.structure.identifierLaboratoire de psychologie [LabPsy]
dc.contributor.authorPOSTAL, Virginie
hal.structure.identifierCentre Hospitalier Universitaire de Bordeaux [CHU de Bordeaux]
dc.contributor.authorBOURDEL‐MARCHASSON, Isabelle
dc.contributor.authorBOISSON, Carole
hal.structure.identifierLaboratoire de psychologie [LabPsy]
dc.contributor.authorMATHEY, Stephanie
ORCID: 0000-0002-5453-8418
IDREF: 066971756
dc.date.accessioned2024-07-05T14:08:51Z
dc.date.available2024-07-05T14:08:51Z
dc.date.issued2012-01-01
dc.identifier.issn2101-6739en_US
dc.identifier.urioai:crossref.org:10.1684/nrp.2012.0209
dc.identifier.urioai:crossref.org:10.3917/rne.042.0123
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/200766
dc.description.abstractCette étude pilote avait pour objectif principal d’évaluer l’effet de la stimulation cognitive sur des processus cognitifs de base (mémoire à court terme et vitesse de traitement) et les principales fonctions exécutives (alternance, inhibition et mise à jour) de patients Alzheimer à un stade léger à modéré. L’objectif secondaire était d’évaluer les bénéfices de l’intervention sur l’état thymique (anxiété, dépression) des patients. Vingt personnes vivant en institution (MMSE entre 20 et 26), ont été réparties aléatoirement dans deux groupes : « stimulation cognitive » et « témoin ». Les patients du groupe stimulation cognitive ont bénéficié durant trois mois de 12 séances d’exercices à visée cognitive et psychosociale. Les résultats ont montré une amélioration des performances aux mesures d’alternance, de mémoire à court terme et de vitesse de traitement, ainsi que de la dépression, pour le groupe stimulation cognitive, comparé au groupe témoin. Les résultats de cette étude soulignent l’intérêt de la stimulation cognitive dans la prise en charge de la maladie d’Alzheimer et tend à confirmer l’hypothèse selon laquelle la plasticité cérébrale reste possible chez les patients Alzheimer durant les premières phases de la maladie.
dc.description.abstractEnThe goal of the present study was to evaluate the efficacy of the cognitive stimulation on elementary cognitive processes and executive functioning in Alzheimer's disease. We hypothesized that cognitive stimulation would decrease cognitive and executive decline dementia-related. Twenty patients with probable Alzheimer's disease (NINCDS-ADRDA criteria) were recruited from a nursing-home (Mini-Mental State Examination score between 20 and 26) and were randomly assigned into an experimental and a control group. Experimental group patients have benefited of 12 sessions of cognitive stimulation in which various cognitive and psychosocial exercises have been performed. Executive functions were assessed by using three tasks that address updating, inhibition and switching abilities. The controlled conditions of executive tasks have been used to measure speed processing and short term memory. Moreover, the impact of cognitive stimulation on anxiety and depression has also been assessed. All patients were evaluated at the study entry and after 12 weeks of the current program. The results show that the experimental group with cognitive stimulation performed better than the control group on processing speed and short-term memory outcomes. As for executive functioning, differences between groups were significant on switching scores. Finally, analyses showed that cognitive stimulated patients differed positively from the control group on depression scales. This pilot study shows the therapeutic benefits of non-pharmacological interventions in patients with Alzheimer's disease. Cognitive stimulation has improved two elementary cognitive components (processing speed and short-term memory) and switching capacities. Our findings also suggest that such intervention can be highly beneficial on depression and tends to show that plasticity remains possible in patients with Alzheimer's disease. In spite of cerebral injury, brain seems to be able to compensate during the early stage of disease.
dc.language.isoFRen_US
dc.sourcecrossref
dc.subjectMaladie d’Alzheimer
dc.subjectTherapie cognitive
dc.subjectFonctions executives
dc.subject.enAlzheimer disease
dc.subject.enCognitive therapy
dc.subject.enExecutive functions
dc.titleStimulation cognitive et fonctions exécutives dans la maladie d’Alzheimer : une étude pilote
dc.title.enCognitive stimulation and executive functions in Alzheimer’s disease: a pilot study
dc.title.alternativeRev Neuropsycholen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1684/nrp.2012.0209en_US
dc.subject.halSciences de l'Homme et Société/Psychologieen_US
bordeaux.journalRevue de neuropsychologieen_US
bordeaux.page123-130en_US
bordeaux.volume4en_US
bordeaux.hal.laboratoriesLaboratoire de psychologie (LabPsy) - UR 4139en_US
bordeaux.issue2en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcedissemin
hal.identifierhal-04637079
hal.version1
hal.date.transferred2024-07-05T14:08:53Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
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dc.rights.ccPas de Licence CCen_US
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