RESCH, Grégory; BRIVES, Charlotte; DEBARBIEUX, Laurent; HODGES, Francesca; KIRCHHELLE, Claas; LAURENT, Frédéric; MOINEAU, Sylvain; MARTINS, Ana Filipa Moreira; ROHDE, Christine

doi:10.1089/phage.2023.0043

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RESCH, Grégory
Centre Hospitalier Universitaire Vaudois = Lausanne University Hospital [Lausanne] [CHUV]

BRIVES, Charlotte
Centre Émile Durkheim [CED]

DEBARBIEUX, Laurent
Bactériophage, bactérie, hôte - Bacteriophage, bacterium, host

Langue

Article de revue

Ce document a été publié dans

PHAGE: Therapy, Applications, and Research. 2024-03-01, vol. 5, n° 1, p. 22-29

Mary Ann Liebert

Résumé en anglais

Despite over a century of collecting bacteriophages, there has been a persistent lack of interest in systematically cataloging resulting phage banks. The result was a situation in which the ongoing growth of phage infrastructures was paralleled by an increasing fragmentation of knowledge about collections' contents and existence. Over the last two decades, renewed interest in phage therapy and phage biology has further exacerbated confusion amid a rapid increase in the number of large and small phage collections and an ongoing dearth of coordination and standardized cataloging. Whatever the modalities (isolated phages or genomes), the time has undoubtedly come to create sustainable, interconnected, and equitable phage banking infrastructures. This article reviews both the history and current status of microbial collections, provides a nonexhaustive overview of relevant phage collections, and reflects on the challenges and potential of centralizing therapeutically relevant collections ahead of likely paradigm shifts caused by synthetic biology and artificial intelligence.< Réduire

Mots clés en anglais

biomedical research

Phage

Biomedical science

Phage therapy

DOI

http://dx.doi.org/10.1089/phage.2023.0043

Project ANR

Des virus pour soigner: le difficile développement d'une innovation biomédicale contre-intuitive - ANR-18-CE36-0001

Origine

Importé de hal

Unités de recherche

Centre Emile Durkheim - Science politique et sociologie comparatives (CED) - UMR 5116