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Genetic Diversity and Population Structure of Mycobacterium bovis at the Human-Animal-Ecosystem Interface in France: “A One Health Approach”

dc.rights.licenseopenen_US
hal.structure.identifierDépartement de Bactériologie-Virologie [CHRU Montpellier]
dc.contributor.authorAPPEGREN, Anaïs
hal.structure.identifierUnité Zoonoses Bactériennes [UZB]
dc.contributor.authorBOSCHIROLI, Maria
hal.structure.identifierUnité Zoonoses Bactériennes [UZB]
dc.contributor.authorDE CRUZ, Krystel
hal.structure.identifierUnité Zoonoses Bactériennes [UZB]
dc.contributor.authorMICHELET, Lorraine
hal.structure.identifierHopital de Bohars - CHRU Brest [CHU - BREST ]
dc.contributor.authorHÉRY-ARNAUD, Geneviève
hal.structure.identifierLaboratoire de Bactériologie [CHU Angers]
dc.contributor.authorKEMPF, Marie
hal.structure.identifierService de bactériologie et d'hygiène hospitalière [Tours]
dc.contributor.authorLANOTTE, Philippe
hal.structure.identifierCentre Hospitalier Universitaire de Nantes = Nantes University Hospital [CHU Nantes]
hal.structure.identifierHôtel-Dieu de Nantes
dc.contributor.authorBEMER, Pascale
hal.structure.identifierMicrobiologie Fondamentale et Pathogénicité [MFP]
dc.contributor.authorPEUCHANT, Olivia
hal.structure.identifierDynamique Microbienne associée aux Infections Urinaires et Respiratoires [DYNAMICURE]
dc.contributor.authorPESTEL-CARON, Martine
hal.structure.identifierDépartement de Microbiologie [CHU Rouen]
dc.contributor.authorSKALLI, Soumaya
hal.structure.identifierPathologies Pulmonaires et Plasticité Cellulaire - UMR-S 1250 [P3CELL]
hal.structure.identifierHôpital universitaire Robert Debré [Reims] [CHU Reims]
dc.contributor.authorBRASME, Lucien
hal.structure.identifierAmpère, Département Energie Electrique [EE]
dc.contributor.authorMARTIN, Christian
hal.structure.identifierCentre Hospitalier Universitaire de Nîmes [CHU Nîmes]
dc.contributor.authorENAULT, Cecilia
hal.structure.identifierCentre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] [CHU ST-E]
dc.contributor.authorCARRICAJO, Anne
hal.structure.identifierInstitut Fédératif de Biologie (IFB)
dc.contributor.authorGUET-REVILLET, Hélène
hal.structure.identifierEurofins Biomnis
dc.contributor.authorPONSODA, Michaël
hal.structure.identifierEurofins Biomnis
dc.contributor.authorJACOMO, Véronique
hal.structure.identifierCentre hospitalier universitaire de Poitiers = Poitiers University Hospital [CHU de Poitiers [La Milétrie]]
dc.contributor.authorBOURGOIN, Anne
hal.structure.identifierLaboratoire CERBA [Saint Ouen l'Aumône]
dc.contributor.authorTROMBERT-PAOLANTONI, Sabine
hal.structure.identifierCHU Montpellier = Montpellier University Hospital
hal.structure.identifierMaladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle [MIVEGEC]
dc.contributor.authorCARRIÈRE, Christian
hal.structure.identifierCHU Montpellier = Montpellier University Hospital
dc.contributor.authorDUPONT, Chloé
hal.structure.identifierCHU Montpellier = Montpellier University Hospital
dc.contributor.authorCONQUET, Guilhem
hal.structure.identifierMaladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle [MIVEGEC]
dc.contributor.authorGALAL, Lokman
hal.structure.identifierMaladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle [MIVEGEC]
dc.contributor.authorBANULS, Anne-Laure
hal.structure.identifierMaladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle [MIVEGEC]
dc.contributor.authorGODREUIL, Sylvain
dc.date.accessioned2024-04-24T11:55:14Z
dc.date.available2024-04-24T11:55:14Z
dc.date.issued2023-04-01
dc.identifier.issn2076-0817en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/199315
dc.description.abstractEnMycobacterium bovis infects cattle and wildlife, and also causes a small proportion of tuberculosis cases in humans. In most European countries, M. bovis infections in cattle have been drastically reduced, but not eradicated. Here, to determine the M. bovis circulation within and between the human, cattle, and wildlife compartments, we characterized by spoligotyping and mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) typing the genetic diversity of M. bovis isolates collected from humans, cattle, and wildlife in France from 2000 to 2010. We also assessed their genetic structure within and among the different host groups, and across time and space. The M. bovis genetic structure and its spatiotemporal variations showed different dynamics in the human and animal compartments. Most genotypes detected in human isolates were absent in cattle and wildlife isolates, possibly because in patients, M. bovis infection was contracted abroad or was the reactivation of an old lesion. Therefore, they did not match the genetic pool present in France during the study period. However, some human-cattle exchanges occurred because some genotypes were common to both compartments. This study provides new elements for understanding M. bovis epidemiology in France, and calls for increased efforts to control this pathogen worldwide.
dc.language.isoENen_US
dc.rights.urihttp://creativecommons.org/licenses/by/
dc.subject.enpopulation genetics
dc.subject.enzoonosis
dc.subject.enOne Health
dc.subject.enFrance
dc.subject.enbovine tuberculosis
dc.title.enGenetic Diversity and Population Structure of Mycobacterium bovis at the Human-Animal-Ecosystem Interface in France: “A One Health Approach”
dc.typeArticle de revueen_US
dc.identifier.doi10.3390/pathogens12040548en_US
dc.subject.halSciences du Vivant [q-bio]en_US
dc.identifier.pubmed37111434en_US
bordeaux.journalPathogensen_US
bordeaux.page548en_US
bordeaux.volume12en_US
bordeaux.hal.laboratoriesMFP (Laboratoire Microbiologie Fondamentale et Pathogénicité) - UMR 5234en_US
bordeaux.issue4en_US
bordeaux.institutionCNRSen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcehal
hal.identifieranses-04265771
hal.version1
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
workflow.import.sourcehal
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Pathogens&rft.date=2023-04-01&rft.volume=12&rft.issue=4&rft.spage=548&rft.epage=548&rft.eissn=2076-0817&rft.issn=2076-0817&rft.au=APPEGREN,%20Ana%C3%AFs&BOSCHIROLI,%20Maria&DE%20CRUZ,%20Krystel&MICHELET,%20Lorraine&H%C3%89RY-ARNAUD,%20Genevi%C3%A8ve&rft.genre=article


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