| dc.rights.license | open | |
| hal.structure.identifier | Institut National de la Santé et de la Recherche Médicale [INSERM] | |
| dc.contributor.author | SIEPMANN, Juergen | |
| hal.structure.identifier | DuPont Health & Nutrition | |
| dc.contributor.author | FAHAM, Amina | |
| hal.structure.identifier | PharmaSolv Consulting | |
| dc.contributor.author | CLAS, Sophie-Dorothée | |
| hal.structure.identifier | Monash Institute of Pharmaceutical Science | |
| dc.contributor.author | BOYD, Ben | |
| dc.contributor.author | JANNIN, Vincent | |
| hal.structure.identifier | Leopold Franzens Universität Innsbruck - University of Innsbruck | |
| dc.contributor.author | BERNKOP-SCHNÜRCH, Andreas | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
| dc.contributor.author | ZHAO, Hang | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
| dc.contributor.author | LECOMMANDOUX, Sebastien | |
| hal.structure.identifier | Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Canada; 9Department of Biochemistry, Faculty of Medicine, University of Toronto | |
| dc.contributor.author | EVANS, James | |
| hal.structure.identifier | Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Canada; 9Department of Biochemistry, Faculty of Medicine, University of Toronto | |
| dc.contributor.author | ALLEN, Christine | |
| hal.structure.identifier | Ludwig Maximilian University [Munich] = Ludwig Maximilians Universität München [LMU] | |
| dc.contributor.author | MERKEL, Olivia | |
| hal.structure.identifier | Ludwig Maximilian University [Munich] = Ludwig Maximilians Universität München [LMU] | |
| dc.contributor.author | COSTABILE, Gabriella | |
| hal.structure.identifier | University of Nottingham, UK [UON] | |
| dc.contributor.author | ALEXANDER, Morgan | |
| hal.structure.identifier | University of Nottingham, UK [UON] | |
| dc.contributor.author | WILDMAN, Ricky | |
| hal.structure.identifier | University of Nottingham, UK [UON] | |
| dc.contributor.author | ROBERTS, Clive | |
| hal.structure.identifier | Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] [ETH Zürich] | |
| dc.contributor.author | LEROUX, Jean-Christophe | |
| dc.date.accessioned | 2020 | |
| dc.date.available | 2020 | |
| dc.date.issued | 2019 | |
| dc.identifier.issn | 0378-5173 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/19896 | |
| dc.description.abstractEn | In pharmaceutical technology, lipids and polymers are considered pillar excipients for the fabrication of most dosage forms, irrespective of the administration route. They play various roles ranging from support vehicles to release rate modifiers, stabilizers, solubilizers, permeation enhancers and transfection agents. Focusing on selected applications, which were discussed at the Annual Scientific Meeting of the Gattefossé Foundation 2018, this manuscript recapitulates the fundamental roles of these two important classes of excipients, either employed alone or in combination, and provides insight on their functional properties in various types of drug formulations. Emphasis is placed on oral formulations for the administration of active pharmaceutical ingredients with low aqueous solubilities or poor permeation properties. Additionally, this review article covers the use of lipids and polymers in the design of colloidal injectable delivery systems, and as substrates in additive manufacturing technologies for the production of tailor-made dosage forms. | |
| dc.language.iso | en | |
| dc.publisher | Elsevier | |
| dc.subject.en | peptides | |
| dc.subject.en | gene delivery | |
| dc.subject.en | polymersomes | |
| dc.subject.en | liposomes | |
| dc.subject.en | solid dispersions | |
| dc.subject.en | self-emulsifying drug delivery systems | |
| dc.subject.en | sustained release | |
| dc.subject.en | 3D printing | |
| dc.title.en | Lipids and polymers in pharmaceutical technology: lifelong companions | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.1016/j.ijpharm.2018.12.080 | |
| dc.subject.hal | Chimie/Polymères | |
| dc.subject.hal | Chimie/Matériaux | |
| dc.subject.hal | Physique [physics]/Matière Condensée [cond-mat]/Matière Molle [cond-mat.soft] | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Sciences pharmaceutiques | |
| bordeaux.journal | International Journal of Pharmaceutics | |
| bordeaux.page | 128-142 | |
| bordeaux.volume | 558 | |
| bordeaux.hal.laboratories | Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629 | * |
| bordeaux.institution | Bordeaux INP | |
| bordeaux.institution | Université de Bordeaux | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-01978128 | |
| hal.version | 1 | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-01978128v1 | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=International%20Journal%20of%20Pharmaceutics&rft.date=2019&rft.volume=558&rft.spage=128-142&rft.epage=128-142&rft.eissn=0378-5173&rft.issn=0378-5173&rft.au=SIEPMANN,%20Juergen&FAHAM,%20Amina&CLAS,%20Sophie-Doroth%C3%A9e&BOYD,%20Ben&JANNIN,%20Vincent&rft.genre=article | |
