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Pichia sorbitophila, an Interspecies Yeast Hybrid, Reveals Early Steps of Genome Resolution After Polyploidization

hal.structure.identifierUniversité de Strasbourg [UNISTRA]
dc.contributor.authorLOUIS, Véronique Leh
hal.structure.identifierUniversité de Strasbourg [UNISTRA]
dc.contributor.authorDESPONS, Laurence
hal.structure.identifierUniversité de Strasbourg [UNISTRA]
dc.contributor.authorFRIEDRICH, Anne
hal.structure.identifierModels and Algorithms for the Genome [ MAGNOME]
dc.contributor.authorMARTIN, Tiphaine
hal.structure.identifierModels and Algorithms for the Genome [ MAGNOME]
dc.contributor.authorDURRENS, Pascal
hal.structure.identifierMICrobiologie de l'ALImentation au Service de la Santé [MICALIS]
hal.structure.identifierAgroParisTech
dc.contributor.authorCASAREGOLA, Serge
hal.structure.identifierMICrobiologie de l'ALImentation au Service de la Santé [MICALIS]
dc.contributor.authorNEUVÉGLISE, Cécile
hal.structure.identifierInstitut de génétique et microbiologie [Orsay] [IGM]
dc.contributor.authorFAIRHEAD, Cécile
hal.structure.identifierInstitut de Biologie et de Technologies de Saclay [IBITECS]
dc.contributor.authorMARCK, Christian
hal.structure.identifierArchitecture et Réactivité de l'ARN [ARN]
dc.contributor.authorCRUZ, José A.
hal.structure.identifierUniversité de Strasbourg [UNISTRA]
dc.contributor.authorSTRAUB, Marie-Laure
hal.structure.identifierGénétique moléculaire, génomique, microbiologie [GMGM]
dc.contributor.authorKUGLER, Valérie
hal.structure.identifierUniversité de Strasbourg [UNISTRA]
dc.contributor.authorSACERDOT, Christine
hal.structure.identifierGénétique moléculaire, génomique, microbiologie [GMGM]
dc.contributor.authorUZUNOV, Zlatyo
hal.structure.identifierBiologie systémique - Systems Biology
dc.contributor.authorTHIERRY, Agnès
hal.structure.identifierMICrobiologie de l'ALImentation au Service de la Santé [MICALIS]
hal.structure.identifierAgroParisTech
dc.contributor.authorWEISS, Stéphanie
hal.structure.identifierArchitecture et Réactivité de l'ARN [ARN]
dc.contributor.authorBLEYKASTEN, Claudine
hal.structure.identifierGénétique moléculaire, génomique, microbiologie [GMGM]
dc.contributor.authorDE MONTIGNY, Jacky
hal.structure.identifierMICrobiologie de l'ALImentation au Service de la Santé [MICALIS]
dc.contributor.authorJACQUES, Noémie
hal.structure.identifierUniversité de Strasbourg [UNISTRA]
dc.contributor.authorJUNG, Paul
hal.structure.identifierGénétique moléculaire des levures [YMG]
dc.contributor.authorLEMAIRE, Marc
hal.structure.identifierMICrobiologie de l'ALImentation au Service de la Santé [MICALIS]
dc.contributor.authorMALLET, Sandrine
hal.structure.identifierMICrobiologie de l'ALImentation au Service de la Santé [MICALIS]
dc.contributor.authorMOREL, Guillaume
hal.structure.identifierGénétique Moléculaire des Levures
dc.contributor.authorRICHARD, Guy-Franck
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
dc.contributor.authorSARKAR, Anasua
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
dc.contributor.authorSAVEL, Guilhem
hal.structure.identifierGénétique moléculaire, génomique, microbiologie [GMGM]
dc.contributor.authorSCHACHERER, Joseph
hal.structure.identifierEarth and Life Institute [Louvain-La-Neuve] [ELI]
dc.contributor.authorSERET, Marie-Line
hal.structure.identifierLaboratoire de chimie bactérienne [LCB]
dc.contributor.authorTALLA, Emmanuel
hal.structure.identifierGenoscope - Centre national de séquençage [Evry] [GENOSCOPE]
dc.contributor.authorSAMSON, Gaëlle
hal.structure.identifierGenoscope - Centre national de séquençage [Evry] [GENOSCOPE]
dc.contributor.authorJUBIN, Claire
hal.structure.identifierInstitut de Génomique d'Evry [IG]
dc.contributor.authorPOULAIN, Julie
hal.structure.identifierGenoscope - Centre national de séquençage [Evry] [GENOSCOPE]
dc.contributor.authorVACHERIE, Benoit
hal.structure.identifierGenoscope - Centre national de séquençage [Evry] [GENOSCOPE]
dc.contributor.authorBARBE, Valérie
hal.structure.identifierGenoscope - Centre national de séquençage [Evry] [GENOSCOPE]
dc.contributor.authorPELLETIER, Eric
hal.structure.identifierUniversité de Strasbourg [UNISTRA]
dc.contributor.authorSHERMAN, David J.
hal.structure.identifierArchitecture et Réactivité de l'ARN [ARN]
dc.contributor.authorWESTHOF, Eric
hal.structure.identifierGenoscope - Centre national de séquençage [Evry] [GENOSCOPE]
dc.contributor.authorWEISSENBACH, Jean
hal.structure.identifierEarth and Life Institute [Louvain-La-Neuve] [ELI]
dc.contributor.authorBARET, Philippe V.
hal.structure.identifierGénomique métabolique [UMR 8030]
hal.structure.identifierInstitut de Génomique d'Evry [IG]
dc.contributor.authorWINCKER, Patrick
hal.structure.identifierMICrobiologie de l'ALImentation au Service de la Santé [MICALIS]
dc.contributor.authorGAILLARDIN, Claude
hal.structure.identifierGénétique Moléculaire des Levures
dc.contributor.authorDUJON, Bernard
hal.structure.identifierGénétique moléculaire, génomique, microbiologie [GMGM]
dc.contributor.authorSOUCIET, Jean-Luc
dc.date.accessioned2024-04-15T09:56:47Z
dc.date.available2024-04-15T09:56:47Z
dc.date.created2012
dc.date.issued2012-02
dc.identifier.issn2160-1836
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/198866
dc.description.abstractEnPolyploidization is an important process in the evolution of eukaryotic genomes, but ensuing molecular mechanisms remain to be clarified. Autopolyploidization or whole-genome duplication events frequently are resolved in resulting lineages by the loss of single genes from most duplicated pairs, causing transient gene dosage imbalance and accelerating speciation through meiotic infertility. Allopolyploidization or formation of interspecies hybrids raises the problem of genetic incompatibility (Bateson-Dobzhansky-Muller effect) and may be resolved by the accumulation of mutational changes in resulting lineages. In this article, we show that an osmotolerant yeast species, Pichia sorbitophila, recently isolated in a concentrated sorbitol solution in industry, illustrates this last situation. Its genome is a mosaic of homologous and homeologous chromosomes, or parts thereof, that corresponds to a recently formed hybrid in the process of evolution. The respective parental contributions to this genome were characterized using existing variations in GC content. The genomic changes that occurred during the short period since hybrid formation were identified (e.g., loss of heterozygosity, unilateral loss of rDNA, reciprocal exchange) and distinguished from those undergone by the two parental genomes after separation from their common ancestor (i.e., NUMT (NUclear sequences of MiTochondrial origin) insertions, gene acquisitions, gene location movements, reciprocal translocation). We found that the physiological characteristics of this new yeast species are determined by specific but unequal contributions of its two parents, one of which could be identified as very closely related to an extant Pichia farinosa strain.
dc.description.sponsorshipHow do genes arise ? Lessons and questions from the evolution of yeast genomes.
dc.language.isoen
dc.publisherGenetics Society of America
dc.rights.urihttp://creativecommons.org/licenses/by/
dc.subjectSACCHAROMYCES-CEREVISIAE
dc.subjectNUCLEOLAR DOMINANCE
dc.subjectEVOLUTION
dc.subject.enHEMIASCOMYCETOUS YEASTS
dc.subject.enCANDIDA-ALBICANS
dc.subject.enDNA-SEQUENCES
dc.subject.enGENE
dc.subject.enGLYCEROL
dc.subject.enHALOTOLERANT
dc.subject.enSPECIATION
dc.title.enPichia sorbitophila, an Interspecies Yeast Hybrid, Reveals Early Steps of Genome Resolution After Polyploidization
dc.typeArticle de revue
dc.identifier.doi10.1534/g3.111.000745
dc.subject.halSciences du Vivant [q-bio]/Microbiologie et Parasitologie/Mycologie
dc.subject.halSciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Génomique, Transcriptomique et Protéomique [q-bio.GN]
bordeaux.journalG3
bordeaux.page299 - 311
bordeaux.volume2
bordeaux.hal.laboratoriesLaboratoire Bordelais de Recherche en Informatique (LaBRI) - UMR 5800*
bordeaux.issue2
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.institutionCNRS
bordeaux.peerReviewedoui
hal.identifierhal-00679348
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-00679348v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=G3&rft.date=2012-02&rft.volume=2&rft.issue=2&rft.spage=299%20-%20311&rft.epage=299%20-%20311&rft.eissn=2160-1836&rft.issn=2160-1836&rft.au=LOUIS,%20V%C3%A9ronique%20Leh&DESPONS,%20Laurence&FRIEDRICH,%20Anne&MARTIN,%20Tiphaine&DURRENS,%20Pascal&rft.genre=article


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