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The complete genome of Blastobotrys (Arxula) adeninivorans LS3 - a yeast of biotechnological interest.

hal.structure.identifierLeibniz Institute of Plant Genetics and Crop Plant Research [Gatersleben] [IPK-Gatersleben]
hal.structure.identifierYeast Genetics
dc.contributor.authorKUNZE, Gotthard
hal.structure.identifierMICrobiologie de l'ALImentation au Service de la Santé [MICALIS]
dc.contributor.authorGAILLARDIN, Claude
hal.structure.identifierInstitute of Plant Biology and Biotechnology
dc.contributor.authorCZERNICKA, Małgorzata
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
hal.structure.identifierModels and Algorithms for the Genome [MAGNOME]
dc.contributor.authorDURRENS, Pascal
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
hal.structure.identifierModels and Algorithms for the Genome [MAGNOME]
dc.contributor.authorMARTIN, Tiphaine
hal.structure.identifierLeibniz Institute of Plant Genetics and Crop Plant Research [Gatersleben] [IPK-Gatersleben]
dc.contributor.authorBÖER, Erik
hal.structure.identifierBioinformatics and Genomics Programme
hal.structure.identifierUniversitat Pompeu Fabra [Barcelona] [UPF]
dc.contributor.authorGABALDÓN, Toni
hal.structure.identifierArchitecture et Réactivité de l'ARN [ARN]
dc.contributor.authorCRUZ, Jose
hal.structure.identifierLaboratoire de chimie bactérienne [LCB]
dc.contributor.authorTALLA, Emmanuel
hal.structure.identifierInstitut de Biologie et de Technologies de Saclay [IBITECS]
dc.contributor.authorMARCK, Christian
hal.structure.identifierUniversité Catholique de Louvain = Catholic University of Louvain [UCL]
dc.contributor.authorGOFFEAU, André
hal.structure.identifierInstitut de Génomique d'Evry [IG]
dc.contributor.authorBARBE, Valérie
hal.structure.identifierEarth and Life Institute [Louvain-La-Neuve] [ELI]
dc.contributor.authorBARET, Philippe
hal.structure.identifierSchool of Biological Sciences
dc.contributor.authorBARONIAN, Keith
hal.structure.identifierLeibniz Institute of Plant Genetics and Crop Plant Research [Gatersleben] [IPK-Gatersleben]
dc.contributor.authorBEIER, Sebastian
hal.structure.identifierArchitecture et Réactivité de l'ARN [ARN]
dc.contributor.authorBLEYKASTEN, Claudine
hal.structure.identifierInstitute of Biochemistry
dc.contributor.authorBODE, Rüdiger
hal.structure.identifierMICrobiologie de l'ALImentation au Service de la Santé [MICALIS]
dc.contributor.authorCASAREGOLA, Serge
hal.structure.identifierUniversité de Strasbourg [UNISTRA]
dc.contributor.authorDESPONS, Laurence
hal.structure.identifierInstitut de génétique et microbiologie [Orsay] [IGM]
dc.contributor.authorFAIRHEAD, Cécile
hal.structure.identifierLeibniz Institute of Plant Genetics and Crop Plant Research [Gatersleben] [IPK-Gatersleben]
dc.contributor.authorGIERSBERG, Martin
hal.structure.identifierLaboratory of Bioinformatics and Protein Engineering
dc.contributor.authorGIERSKI, Przemysław Piotr
hal.structure.identifierLeibniz Institute of Plant Genetics and Crop Plant Research [Gatersleben] [IPK-Gatersleben]
dc.contributor.authorHÄHNEL, Urs
hal.structure.identifierLeibniz Institute of Plant Genetics and Crop Plant Research [Gatersleben] [IPK-Gatersleben]
dc.contributor.authorHARTMANN, Anja
hal.structure.identifierLeibniz Institute of Plant Genetics and Crop Plant Research [Gatersleben] [IPK-Gatersleben]
dc.contributor.authorJANKOWSKA, Dagmara
hal.structure.identifierGénomique métabolique [UMR 8030]
dc.contributor.authorJUBIN, Claire
hal.structure.identifierGénétique moléculaire, génomique, microbiologie [GMGM]
dc.contributor.authorJUNG, Paul
hal.structure.identifierGénétique Moléculaire des Levures
dc.contributor.authorLAFONTAINE, Ingrid
hal.structure.identifierGénétique moléculaire, génomique, microbiologie [GMGM]
dc.contributor.authorLEH-LOUIS, Véronique
hal.structure.identifierGénétique moléculaire des levures [YMG]
dc.contributor.authorLEMAIRE, Marc
hal.structure.identifierBioinformatics and Genomics Programme
hal.structure.identifierUniversitat Pompeu Fabra [Barcelona] [UPF]
dc.contributor.authorMARCET-HOUBEN, Marina
hal.structure.identifierLeibniz Institute of Plant Genetics and Crop Plant Research [Gatersleben] [IPK-Gatersleben]
dc.contributor.authorMASCHER, Martin
hal.structure.identifierMICrobiologie de l'ALImentation au Service de la Santé [MICALIS]
dc.contributor.authorMOREL, Guillaume
hal.structure.identifierGénétique Moléculaire des Levures
dc.contributor.authorRICHARD, Guy-Franck
hal.structure.identifierLeibniz Institute of Plant Genetics and Crop Plant Research [Gatersleben] [IPK-Gatersleben]
dc.contributor.authorRIECHEN, Jan
hal.structure.identifierGénétique Moléculaire des Levures
dc.contributor.authorSACERDOT, Christine
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
dc.contributor.authorSARKAR, Anasua
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
dc.contributor.authorSAVEL, Guilhem
hal.structure.identifierGénétique moléculaire, génomique, microbiologie [GMGM]
dc.contributor.authorSCHACHERER, Joseph
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
hal.structure.identifierModels and Algorithms for the Genome [MAGNOME]
dc.contributor.authorSHERMAN, David
hal.structure.identifierLeibniz Institute of Plant Genetics and Crop Plant Research [Gatersleben] [IPK-Gatersleben]
dc.contributor.authorSTEIN, Nils
hal.structure.identifierGénétique moléculaire, génomique, microbiologie [GMGM]
dc.contributor.authorSTRAUB, Marie-Laure
hal.structure.identifierGénétique Moléculaire des Levures
dc.contributor.authorTHIERRY, Agnès
hal.structure.identifierLeibniz Institute of Plant Genetics and Crop Plant Research [Gatersleben] [IPK-Gatersleben]
dc.contributor.authorTRAUTWEIN-SCHULT, Anke
hal.structure.identifierInstitut de Génomique d'Evry [IG]
dc.contributor.authorVACHERIE, Benoit
hal.structure.identifierArchitecture et Réactivité de l'ARN [ARN]
dc.contributor.authorWESTHOF, Eric
hal.structure.identifierLeibniz Institute of Plant Genetics and Crop Plant Research [Gatersleben] [IPK-Gatersleben]
dc.contributor.authorWORCH, Sebastian
hal.structure.identifierGénétique Moléculaire des Levures
dc.contributor.authorDUJON, Bernard
hal.structure.identifierGénétique moléculaire, génomique, microbiologie [GMGM]
dc.contributor.authorSOUCIET, Jean-Luc
hal.structure.identifierInstitut de Génomique d'Evry [IG]
dc.contributor.authorWINCKER, Patrick
hal.structure.identifierLeibniz Institute of Plant Genetics and Crop Plant Research [Gatersleben] [IPK-Gatersleben]
dc.contributor.authorSCHOLZ, Uwe
hal.structure.identifierMICrobiologie de l'ALImentation au Service de la Santé [MICALIS]
dc.contributor.authorNEUVÉGLISE, Cécile
dc.date.accessioned2024-04-15T09:41:23Z
dc.date.available2024-04-15T09:41:23Z
dc.date.issued2014
dc.identifier.issn1754-6834
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/197596
dc.description.abstractEnBACKGROUND: The industrially important yeast Blastobotrys (Arxula) adeninivorans is an asexual hemiascomycete phylogenetically very distant from Saccharomyces cerevisiae. Its unusual metabolic flexibility allows it to use a wide range of carbon and nitrogen sources, while being thermotolerant, xerotolerant and osmotolerant. RESULTS: The sequencing of strain LS3 revealed that the nuclear genome of A. adeninivorans is 11.8 Mb long and consists of four chromosomes with regional centromeres. Its closest sequenced relative is Yarrowia lipolytica, although mean conservation of orthologs is low. With 914 introns within 6116 genes, A. adeninivorans is one of the most intron-rich hemiascomycetes sequenced to date. Several large species-specific families appear to result from multiple rounds of segmental duplications of tandem gene arrays, a novel mechanism not yet described in yeasts. An analysis of the genome and its transcriptome revealed enzymes with biotechnological potential, such as two extracellular tannases (Atan1p and Atan2p) of the tannic-acid catabolic route, and a new pathway for the assimilation of n-butanol via butyric aldehyde and butyric acid. CONCLUSIONS: The high-quality genome of this species that diverged early in Saccharomycotina will allow further fundamental studies on comparative genomics, evolution and phylogenetics. Protein components of different pathways for carbon and nitrogen source utilization were identified, which so far has remained unexplored in yeast, offering clues for further biotechnological developments. In the course of identifying alternative microorganisms for biotechnological interest, A. adeninivorans has already proved its strengthened competitiveness as a promising cell factory for many more applications.
dc.language.isoen
dc.publisherBioMed Central
dc.subjectn-butanol
dc.subjectbiotechnology
dc.subject.enyeast
dc.subject.engenome
dc.subject.entannic acid
dc.subject.enmetabolism
dc.title.enThe complete genome of Blastobotrys (Arxula) adeninivorans LS3 - a yeast of biotechnological interest.
dc.typeArticle de revue
dc.identifier.doi10.1186/1754-6834-7-66
dc.subject.halSciences du Vivant [q-bio]/Biotechnologies
dc.subject.halInformatique [cs]/Biotechnologie
bordeaux.journalBiotechnology for Biofuels
bordeaux.page66
bordeaux.volume7
bordeaux.hal.laboratoriesLaboratoire Bordelais de Recherche en Informatique (LaBRI) - UMR 5800*
bordeaux.issue1
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.institutionCNRS
bordeaux.peerReviewedoui
hal.identifierpasteur-00988609
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//pasteur-00988609v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Biotechnology%20for%20Biofuels&rft.date=2014&rft.volume=7&rft.issue=1&rft.spage=66&rft.epage=66&rft.eissn=1754-6834&rft.issn=1754-6834&rft.au=KUNZE,%20Gotthard&GAILLARDIN,%20Claude&CZERNICKA,%20Ma%C5%82gorzata&DURRENS,%20Pascal&MARTIN,%20Tiphaine&rft.genre=article


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