Stochastic spontaneous calcium release events trigger premature ventricular complexes by overcoming electrotonic load
dc.contributor.author | CAMPOS, Fernando | |
hal.structure.identifier | California State University [Northridge] [CSUN] | |
dc.contributor.author | SHIFERAW, Yohannes | |
dc.contributor.author | PRASSL, Anton | |
hal.structure.identifier | Johns Hopkins University [JHU] | |
dc.contributor.author | BOYLE, Patrick | |
hal.structure.identifier | Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN] | |
dc.contributor.author | VIGMOND, Edward | |
hal.structure.identifier | European Space Research and Technology Centre [ESTEC] | |
dc.contributor.author | PLANK, Gernot | |
dc.date.accessioned | 2024-04-04T02:51:06Z | |
dc.date.available | 2024-04-04T02:51:06Z | |
dc.date.issued | 2015-07-01 | |
dc.identifier.issn | 0008-6363 | |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/191967 | |
dc.description.abstractEn | Premature ventricular complexes (PVCs) due to spontaneous calcium (Ca) release (SCR) events at the cell level can precipitate ventricular arrhythmias. However, the mechanistic link between SCRs and PVC formation remains incompletely understood. The aim of this study was to investigate the conditions under which delayed afterdepolarizations resulting from stochastic subcellular SCR events can overcome electrotonic source-sink mismatch, leading to PVC initiation. | |
dc.language.iso | en | |
dc.publisher | Oxford University Press (OUP) | |
dc.subject.en | Delayed afterdepolarization | |
dc.subject.en | Computer-based model | |
dc.subject.en | Triggered activity | |
dc.subject.en | Purkinje system | |
dc.subject.en | Arrhythmia | |
dc.title.en | Stochastic spontaneous calcium release events trigger premature ventricular complexes by overcoming electrotonic load | |
dc.type | Article de revue | |
dc.identifier.doi | 10.1093/cvr/cvv149 | |
dc.subject.hal | Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Biophysique | |
dc.subject.hal | Sciences du Vivant [q-bio]/Médecine humaine et pathologie/Cardiologie et système cardiovasculaire | |
bordeaux.journal | Cardiovascular Research | |
bordeaux.page | 175-183 | |
bordeaux.volume | 107 | |
bordeaux.hal.laboratories | Institut de Mathématiques de Bordeaux (IMB) - UMR 5251 | * |
bordeaux.issue | 1 | |
bordeaux.institution | Université de Bordeaux | |
bordeaux.institution | Bordeaux INP | |
bordeaux.institution | CNRS | |
bordeaux.peerReviewed | oui | |
hal.identifier | hal-02886267 | |
hal.version | 1 | |
hal.popular | non | |
hal.audience | Internationale | |
hal.origin.link | https://hal.archives-ouvertes.fr//hal-02886267v1 | |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Cardiovascular%20Research&rft.date=2015-07-01&rft.volume=107&rft.issue=1&rft.spage=175-183&rft.epage=175-183&rft.eissn=0008-6363&rft.issn=0008-6363&rft.au=CAMPOS,%20Fernando&SHIFERAW,%20Yohannes&PRASSL,%20Anton&BOYLE,%20Patrick&VIGMOND,%20Edward&rft.genre=article |
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