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Fibrosis and Conduction Abnormalities as Basis for Overlap of Brugada Syndrome and Early Repolarization Syndrome
| hal.structure.identifier | Department of Experimental Cardiology, Amsterdam University Medical Center | |
| hal.structure.identifier | Department of Medical Biology, Amsterdam University Medical Center | |
| dc.contributor.author | BOUKENS, Bastiaan | |
| hal.structure.identifier | IHU-LIRYC | |
| hal.structure.identifier | Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN] | |
| hal.structure.identifier | Institut de Mathématiques de Bordeaux [IMB] | |
| dc.contributor.author | POTSE, Mark | |
| hal.structure.identifier | Department of Experimental Cardiology, Amsterdam University Medical Center | |
| dc.contributor.author | CORONEL, Ruben | |
| dc.date.accessioned | 2024-04-04T02:47:26Z | |
| dc.date.available | 2024-04-04T02:47:26Z | |
| dc.date.issued | 2021-02-04 | |
| dc.identifier.issn | 1661-6596 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/191639 | |
| dc.description.abstractEn | Brugada syndrome and early repolarization syndrome are both classified as J-wave syndromes, with a similar mechanism of arrhythmogenesis and with the same basis for genesis of the characteristic electrocardiographic features. The Brugada syndrome is now considered a conduction disorder based on subtle structural abnormalities in the right ventricular outflow tract. Recent evidence suggests structural substrate in patients with the early repolarization syndrome as well. We propose a unifying mechanism based on these structural abnormalities explaining both arrhythmogenesis and the electrocardiographic changes. In addition, we speculate that, with increasing technical advances in imaging techniques and their spatial resolution, these syndromes will be reclassified as structural heart diseases or cardiomyopathies. | |
| dc.description.sponsorship | L'Institut de Rythmologie et modélisation Cardiaque - ANR-10-IAHU-0004 | |
| dc.language.iso | en | |
| dc.publisher | MDPI | |
| dc.subject.en | Arrhythmias | |
| dc.subject.en | Brugada syndrome | |
| dc.subject.en | Early repolarization pattern | |
| dc.subject.en | Fibrosis | |
| dc.subject.en | Conduction | |
| dc.subject.en | Repolarization | |
| dc.title.en | Fibrosis and Conduction Abnormalities as Basis for Overlap of Brugada Syndrome and Early Repolarization Syndrome | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.3390/ijms22041570 | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Médecine humaine et pathologie/Cardiologie et système cardiovasculaire | |
| bordeaux.journal | International Journal of Molecular Sciences | |
| bordeaux.page | 1570 | |
| bordeaux.volume | 22 | |
| bordeaux.hal.laboratories | Institut de Mathématiques de Bordeaux (IMB) - UMR 5251 | * |
| bordeaux.issue | 4 | |
| bordeaux.institution | Université de Bordeaux | |
| bordeaux.institution | Bordeaux INP | |
| bordeaux.institution | CNRS | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-03133273 | |
| hal.version | 1 | |
| hal.popular | non | |
| hal.audience | Internationale | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-03133273v1 | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=International%20Journal%20of%20Molecular%20Sciences&rft.date=2021-02-04&rft.volume=22&rft.issue=4&rft.spage=1570&rft.epage=1570&rft.eissn=1661-6596&rft.issn=1661-6596&rft.au=BOUKENS,%20Bastiaan&POTSE,%20Mark&CORONEL,%20Ruben&rft.genre=article |
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