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hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorEPHERRE, Romain
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorGOGLIO, Graziella
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorMORNET, Stéphane
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorDUGUET, Etienne
dc.contributor.editorPaul Ducheyne
dc.date.accessioned2023-11-20T17:27:53Z
dc.date.available2023-11-20T17:27:53Z
dc.date.issued2011
dc.identifier.isbn978-0-08-055302-3
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/185923
dc.description.abstractEnMagnetic nanoparticles (MNPs) have attracted attention in modern medicine and pharmacology because of their potential usefulness as contrast agents for magnetic resonance imaging (MRI), as colloidal mediators for cancer magnetic hyperthermia or as active constituents of drug delivery platforms. This review examines these in vivo applications through an understanding of the involved problems and the current and future possibilities for resolving them. A special emphasis is made on MNP requirements from a physical viewpoint (e.g., relaxivity for MRI, specific absorption rate for hyperthermia, magnetic guidance), the factors affecting their biodistribution after intravenous injection (e.g., size, colloidal stability, surface hydrophobic/hydrophilic balance) and the solutions envisaged for enhancing their half-life in the blood compartment and targeting tumor cells.
dc.language.isoen
dc.publisherElsevier
dc.publisher.locationAmsterdam
dc.source.titleComprehensive Biomaterials
dc.subject.enBiofunctionalization
dc.subject.enBiomedical applications
dc.subject.enCancer
dc.subject.enContrast agent
dc.subject.enDrug delivery
dc.subject.enHyperthermia
dc.subject.enMagnetic fluids
dc.subject.enMagnetic guidance
dc.subject.enMagnetic nanoparticles
dc.subject.enMagnetic resonance imaging
dc.subject.enStealthiness
dc.subject.enSynthesis
dc.subject.enTargeting
dc.title.enHybrid Magnetic Nanoparticles for Targeted Delivery
dc.typeChapitre d'ouvrage
dc.identifier.doi10.1016/B978-0-08-055294-1.00145-8
dc.subject.halChimie/Matériaux
bordeaux.page575-593
bordeaux.hal.laboratoriesInstitut de Chimie de la Matière Condensée de Bordeaux (ICMCB) - UMR 5026*
bordeaux.issue4
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.institutionCNRS
bordeaux.title.proceedingComprehensive Biomaterials
hal.identifierhal-04161666
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-04161666v1
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