A Novel Tool to Identify Bactericidal Compounds against Vulnerable Targets in Drug-Tolerant M. tuberculosis found in Caseum
hal.structure.identifier | Public Health Research Institute [Newark] [PHRI] | |
dc.contributor.author | SARATHY, Jansy | |
hal.structure.identifier | City University of Hong Kong [Hong Kong] [CUHK] | |
dc.contributor.author | XIE, Min | |
hal.structure.identifier | University of Kent [Canterbury] | |
dc.contributor.author | JONES, Richard | |
hal.structure.identifier | Cornell University [New York] | |
dc.contributor.author | CHANG, Adrienne | |
hal.structure.identifier | Hackensack Meridian Health | |
dc.contributor.author | OSIECKI, Paulina | |
hal.structure.identifier | National Institute of Allergy and Infectious Diseases [Bethesda] [NIAID-NIH] | |
dc.contributor.author | WEINER, Danielle | |
hal.structure.identifier | Hackensack Meridian Health | |
dc.contributor.author | TSAO, Wen-Shan | |
hal.structure.identifier | Hackensack Meridian Health | |
dc.contributor.author | DOUGHER, Maureen | |
hal.structure.identifier | Chimie et Biologie des Membranes et des Nanoobjets [CBMN] | |
dc.contributor.author | BLANC, Landry | |
hal.structure.identifier | Global Alliance for TB Drug Development | |
dc.contributor.author | FOTOUHI, Nader | |
hal.structure.identifier | National Institute of Allergy and Infectious Diseases [Bethesda] [NIAID-NIH] | |
dc.contributor.author | VIA, Laura | |
hal.structure.identifier | National Institute of Allergy and Infectious Diseases [Bethesda] [NIAID-NIH] | |
dc.contributor.author | BARRY, Clifton | |
hal.structure.identifier | Cornell University [New York] | |
dc.contributor.author | DE VLAMINCK, Iwijn | |
hal.structure.identifier | Pleiade, from patterns to models in computational biodiversity and biotechnology [PLEIADE] | |
dc.contributor.author | SHERMAN, David James | |
hal.structure.identifier | Hackensack Meridian Health | |
dc.contributor.author | DARTOIS, Véronique | |
dc.date.accessioned | 2023-11-20T17:23:58Z | |
dc.date.available | 2023-11-20T17:23:58Z | |
dc.date.issued | 2023-04-25 | |
dc.identifier.issn | 2161-2129 | |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/185696 | |
dc.description.abstractEn | M. tuberculosis (Mtb) within the caseous core of necrotic granulomas and cavities is extremely drug tolerant and presents a significant hurdle to treatment success and relapse prevention. Many in vitro models of nonreplicating persistence have been developed to characterize the physiologic and metabolic adaptations of Mtb and identify compounds active against this treatment-recalcitrant population. | |
dc.language.iso | en | |
dc.publisher | American Society for Microbiology | |
dc.title.en | A Novel Tool to Identify Bactericidal Compounds against Vulnerable Targets in Drug-Tolerant M. tuberculosis found in Caseum | |
dc.type | Article de revue | |
dc.identifier.doi | 10.1128/mbio.00598-23 | |
dc.subject.hal | Sciences du Vivant [q-bio]/Sciences pharmaceutiques/Pharmacologie | |
bordeaux.journal | mBio | |
bordeaux.volume | 14 | |
bordeaux.hal.laboratories | BioGeCo (Biodiversité Gènes & Communautés) - UMR 1202 | * |
bordeaux.issue | 2 | |
bordeaux.institution | Université de Bordeaux | |
bordeaux.institution | INRAE | |
bordeaux.peerReviewed | oui | |
hal.identifier | hal-04248670 | |
hal.version | 1 | |
hal.popular | non | |
hal.audience | Internationale | |
hal.origin.link | https://hal.archives-ouvertes.fr//hal-04248670v1 | |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=mBio&rft.date=2023-04-25&rft.volume=14&rft.issue=2&rft.eissn=2161-2129&rft.issn=2161-2129&rft.au=SARATHY,%20Jansy&XIE,%20Min&JONES,%20Richard&CHANG,%20Adrienne&OSIECKI,%20Paulina&rft.genre=article |
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