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dc.rights.licenseopenen_US
hal.structure.identifierMicrobiologie Fondamentale et Pathogénicité [MFP]
dc.contributor.authorRAPISARDA, Chiara
hal.structure.identifierInstitut Européen de Chimie et Biologie [IECB]
hal.structure.identifierMicrobiologie Fondamentale et Pathogénicité [MFP]
hal.structure.identifierInstitute of Structural and Molecular Biology
dc.contributor.authorFRONZES, Remi
dc.date.accessioned2023-11-20T15:17:36Z
dc.date.available2023-11-20T15:17:36Z
dc.date.issued2018-01-01
dc.identifier.issn1467-3045en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/184855
dc.description.abstractEnIn this review we examine the use of secretion systems by bacteria to subvert host functions. Bacteria have evolved multiple systems to interact with and overcome their eukaryotic host and other prokaryotes. Secretion systems are required for the release of several effectors through the bacterial membrane(s) into the extracellular space or directly into the cytoplasm of the host. We review the secretion systems of Gram-positive and Gram-negative bacteria and describe briefly the structural composition of the seven secretion systems that have been associated with increased virulence through subversion of host functions. Some of the effects of such systems on eukaryotic host processes have been studied extensively. We also describe the best-characterized effectors of each secretion system to give an overview of the molecular mechanisms employed by bacteria to hide from the immune system and convert eukaryotic cells into optimal ecological niches for their replication.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enAnimals
dc.subject.enBacterial Proteins
dc.subject.enBacterial Secretion Systems
dc.subject.enEukaryotic Cells
dc.subject.enGene Expression Regulation
dc.subject.enBacterial
dc.subject.enGram-Negative Bacteria
dc.subject.enGram-Positive Bacteria
dc.subject.enHost-Pathogen Interactions
dc.subject.enHumans
dc.subject.enModels
dc.subject.enMolecular
dc.subject.enPeriplasm
dc.subject.enProtein Structure
dc.subject.enSecondary
dc.subject.enProtein Transport
dc.subject.enVirulence
dc.subject.enVirulence Factors
dc.title.enSecretion Systems Used by Bacteria to Subvert Host Functions.
dc.title.alternativeCurr Issues Mol Biolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.21775/cimb.025.001en_US
dc.subject.halSciences du Vivant [q-bio]/Microbiologie et Parasitologieen_US
dc.identifier.pubmed28875938en_US
bordeaux.journalCurrent Issues in Molecular Biologyen_US
bordeaux.page1-42en_US
bordeaux.volume25en_US
bordeaux.hal.laboratoriesMFP (Laboratoire Microbiologie Fondamentale et Pathogénicité) - UMR 5234en_US
bordeaux.institutionCNRSen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcepubmed
hal.identifierhal-04296186
hal.version1
hal.date.transferred2023-11-20T15:17:38Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
workflow.import.sourcepubmed
dc.rights.ccPas de Licence CCen_US
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