An Alternative Maze to Assess Novel Object Recognition in Mice
| dc.rights.license | open | en_US |
| hal.structure.identifier | Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB] | |
| dc.contributor.author | OLIVEIRA DA CRUZ, Jose Fernando | |
| hal.structure.identifier | Universitat Pompeu Fabra [Barcelona] [UPF] | |
| dc.contributor.author | GOMIS-GONZALEZ, Maria | |
| hal.structure.identifier | Universitat Pompeu Fabra [Barcelona] [UPF] | |
| dc.contributor.author | MALDONADO, Rafael | |
| hal.structure.identifier | Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB] | |
| dc.contributor.author | MARSICANO, Giovanni | |
| hal.structure.identifier | Universitat Pompeu Fabra [Barcelona] [UPF] | |
| dc.contributor.author | OZAITA, Andres | |
| hal.structure.identifier | Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB] | |
| dc.contributor.author | BUSQUETS-GARCIA, Arnau | |
| dc.date.accessioned | 2023-06-14T07:55:03Z | |
| dc.date.available | 2023-06-14T07:55:03Z | |
| dc.date.issued | 2020-06-20 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/182672 | |
| dc.description.abstractEn | The novel object recognition (NOR) task is a behavioral test commonly used to evaluate episodic-like declarative memory and it relies on the innate tendency of rodents to explore novelty. Here we present a maze used to evaluate NOR memory in mice that reduces the time of the assay while improving reliability of the measurements by increasing the exploratory behavior. This memory test, being performed in a two-arms maze, is suitable for several strains of mice (including inbreed and outbreed) and does not require extended training sessions allowing an accurate temporal assessment of memory formation. This particular maze increases the mouse exploration time and reduces variability compared to other arenas used before to assess NOR. As both long- and short-term NOR memory can be easily and accurately quantified using this paradigm, this improved methodology can be easily applied to study pharmacological, genetic or age-related modulation of cognitive function. Copyright © 2020 The Authors; exclusive licensee Bio-protocol LLC. | |
| dc.description.sponsorship | Initiative d'excellence de l'Université de Bordeaux - ANR-10-IDEX-0003 | en_US |
| dc.language.iso | EN | en_US |
| dc.subject.en | Novel Object recognition memory | |
| dc.subject.en | Cognition | |
| dc.subject.en | Mouse behavior | |
| dc.subject.en | Memory task | |
| dc.subject.en | Learning | |
| dc.subject.en | Animal behavior | |
| dc.title.en | An Alternative Maze to Assess Novel Object Recognition in Mice | |
| dc.title.alternative | Bio Protoc | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.21769/BioProtoc.3651 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC] | en_US |
| dc.identifier.pubmed | 33659321 | en_US |
| bordeaux.journal | Bio-protocol | en_US |
| bordeaux.volume | 10 | en_US |
| bordeaux.hal.laboratories | Neurocentre Magendie - U1215 | en_US |
| bordeaux.issue | 12 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | Endocannabinoïdes et Neuroadaptation | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.identifier.funderID | Ministerio de Economía y Competitividad | en_US |
| hal.identifier | hal-04127713 | |
| hal.version | 1 | |
| hal.date.transferred | 2023-06-14T07:55:10Z | |
| hal.export | true | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Bio-protocol&rft.date=2020-06-20&rft.volume=10&rft.issue=12&rft.au=OLIVEIRA%20DA%20CRUZ,%20Jose%20Fernando&GOMIS-GONZALEZ,%20Maria&MALDONADO,%20Rafael&MARSICANO,%20Giovanni&OZAITA,%20Andres&rft.genre=article |
