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dc.rights.licenseopenen_US
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorAHMED OMAR, Naima
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorAMEDEE, Joelle
ORCID: 0000-0002-4888-0129
IDREF: 87485605
dc.contributor.authorLETOURNEUR, Didier
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorFRICAIN, Jean-Christophe
ORCID: 0000-0001-7855-6437
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorFENELON, Mathilde
dc.date.accessioned2023-04-06T15:51:13Z
dc.date.available2023-04-06T15:51:13Z
dc.date.issued2022
dc.identifier.issn2296-4185en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/172862
dc.description.abstractEnBone tissue engineering (BTE) strategies are increasingly investigated to overcome the limitations of currently used bone substitutes and to improve the bone regeneration process. Among the natural polymers used for tissue engineering, dextran and pullulan appear as natural hydrophilic polysaccharides that became promising biomaterials for BTE. This systematic review aimed to present the different published applications of pullulan and dextran-based biomaterials for BTE. An electronic search in Pubmed, Scopus, and Web of Science databases was conducted. Selection of articles was performed following PRISMA guidelines. This systematic review led to the inclusion of 28 articles on the use of pullulan and/or dextran-based biomaterials to promote bone regeneration in preclinical models. Sixteen studies focused on dextran-based materials for bone regeneration, six on pullulan substitutes and six on the combination of pullulan and dextran. Several strategies have been developed to provide bone regeneration capacity, mainly through their fabrication processes (functionalization methods, cross-linking process), or the addition of bioactive elements. We have summarized here the strategies employed to use the polysaccharide scaffolds (fabrication process, composition, application usages, route of administration), and we highlighted their relevance and limitations for BTE applications.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enpullulan
dc.subject.endextran
dc.subject.enbone tissue engineering
dc.subject.ennatural polymers
dc.subject.enpolysaccharides
dc.subject.enbone regeneration
dc.title.enRecent Advances of Pullulan and/or Dextran-Based Materials for Bone Tissue Engineering Strategies in Preclinical Studies: A Systematic Review
dc.title.alternativeFront. Bioeng. Biotechnol.en_US
dc.typeArticle de revueen_US
dc.identifier.doi10.3389/fbioe.2022.889481en_US
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologieen_US
bordeaux.journalFrontiers in Bioengineering and Biotechnologyen_US
bordeaux.volume10en_US
bordeaux.hal.laboratoriesBioingénierie Tissulaire (BioTis) - U1026en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.institutionINSERMen_US
bordeaux.institutionCHU de Bordeauxen_US
bordeaux.institutionInstitut Bergoniéen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-04061399
hal.version1
hal.date.transferred2023-04-06T15:51:26Z
hal.exporttrue
dc.rights.ccCC BYen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Frontiers%20in%20Bioengineering%20and%20Biotechnology&rft.date=2022&rft.volume=10&rft.eissn=2296-4185&rft.issn=2296-4185&rft.au=AHMED%20OMAR,%20Naima&AMEDEE,%20Joelle&LETOURNEUR,%20Didier&FRICAIN,%20Jean-Christophe&FENELON,%20Mathilde&rft.genre=article


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