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Direct medical cost of bipolar disorder: Insights from the FACE-BD longitudinal cohort

dc.rights.licenseopenen_US
hal.structure.identifierFondation FondaMental [Créteil]
hal.structure.identifierCHU Henri Mondor [Créteil]
hal.structure.identifierIMRB - "Neuropsychiatrie translationnelle" [Créteil] [U955 Inserm - UPEC]
dc.contributor.authorLAIDI, Charles
hal.structure.identifierFondation FondaMental [Créteil]
hal.structure.identifierCHU Henri Mondor [Créteil]
hal.structure.identifierIMRB - "Neuropsychiatrie translationnelle" [Créteil] [U955 Inserm - UPEC]
dc.contributor.authorGODIN, Ophelia
hal.structure.identifierHôpital Lariboisière-Fernand-Widal [APHP]
hal.structure.identifierFondation FondaMental [Créteil]
hal.structure.identifierUniversité Paris Cité [UPCité]
hal.structure.identifierOptimisation thérapeutique en Neuropsychopharmacologie [OPTeN (UMR_S 1144 / U1144)]
dc.contributor.authorETAIN, Bruno
hal.structure.identifierHôpital Lariboisière-Fernand-Widal [APHP]
hal.structure.identifierFondation FondaMental [Créteil]
hal.structure.identifierUniversité Paris Cité [UPCité]
hal.structure.identifierOptimisation thérapeutique en Neuropsychopharmacologie [OPTeN (UMR_S 1144 / U1144)]
dc.contributor.authorBELLIVIER, Frank
hal.structure.identifierCHU Henri Mondor [Créteil]
dc.contributor.authorELANDALOUSSI, Yannis
hal.structure.identifierCentre Hospitalier Régional Universitaire [Montpellier] [CHRU Montpellier]
hal.structure.identifierFondation FondaMental [Créteil]
hal.structure.identifierInstitut de Génomique Fonctionnelle [IGF]
dc.contributor.authorOLIE, Emilie
hal.structure.identifierCentre hospitalier Charles Perrens [Bordeaux]
hal.structure.identifierFondation FondaMental [Créteil]
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorAOUIZERATE, Bruno
hal.structure.identifierCentre hospitalier Charles Perrens [Bordeaux]
hal.structure.identifierFondation FondaMental [Créteil]
dc.contributor.authorGARD, Sebastien
hal.structure.identifierCentre hospitalier Charles Perrens [Bordeaux]
hal.structure.identifierFondation FondaMental [Créteil]
dc.contributor.authorLOFTUS, Josephine
hal.structure.identifierInstitut de Neurosciences de la Timone [INT]
hal.structure.identifierFondation FondaMental [Créteil]
hal.structure.identifierCentre Hospitalier Princesse Grace
dc.contributor.authorBELZEAUX, Raoul
dc.contributor.authorDUBERTRET, C.
dc.contributor.authorLAOUAMRI, H.
dc.contributor.authorPASSERIEUX, C.
dc.contributor.authorPELLETIER, A.
dc.contributor.authorPOLOSAN, M.
dc.contributor.authorSCHWAN, R.
dc.contributor.authorSAMALIN, L.
dc.contributor.authorLLORCA, P.-M.
dc.contributor.authorCOURTET, P.
dc.contributor.authorDURAND-ZALESKI, I.
dc.contributor.authorLEBOYER, M.
dc.date.accessioned2023-02-13T15:21:39Z
dc.date.available2023-02-13T15:21:39Z
dc.date.issued2022-06
dc.identifier.issn0165-0327en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/171939
dc.description.abstractEnBackground: Bipolar disorder (BD) is a severe chronic psychiatric disorder affecting 0.5 to 1% of the population worldwide. To date, most studies have estimated the cost of BD via information sourced from insurance claims with limited information on clinical characteristics and course of BD. The aims of this study are (i) to estimate the direct healthcare cost associated with BD and to identify contributing factors and (ii) to study the evolution of cost during a two-year follow-up period. Method: We analyzed a sample of 1116 individuals with BD included in the Advanced Centers of Expertise in Bipolar Disorder cohort. We estimated the direct healthcare cost per year and per patient, and we identified the clinical features of patients with BD associated with higher direct healthcare costs. In a subsample of patients followed up for two years centers of expertise for BD, we studied the evolution of direct healthcare cost. Results: The average cost of bipolar disorder was € 6910 per year and per patient. Clinical features of BD, sociodemographic characteristics, and associated addiction were associated with higher direct healthcare costs. In the subsample of patients followed-up for two years, direct healthcare cost dropped by more than 50%, strongly suggesting the beneficial effect of specialized care organization. Limitation: We did not estimate indirect healthcare and intangible costs. Conclusion: Our study investigates the cost of BD and its evolution in a deeply phenotyped longitudinal sample. Cost-utility and cost-effectiveness analyses are required to inform resource allocation decisions and to promote innovative healthcare organizations. © 2022
dc.description.sponsorshipSorbonne Universités à Paris pour l'Enseignement et la Rechercheen_US
dc.description.sponsorshipFondaMental-Cohortes - ANR-10-COHO-0010en_US
dc.language.isoENen_US
dc.title.enDirect medical cost of bipolar disorder: Insights from the FACE-BD longitudinal cohort
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.jad.2022.02.071en_US
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]en_US
dc.identifier.pubmed35248665en_US
bordeaux.journalJournal of Affective Disordersen_US
bordeaux.page223-231en_US
bordeaux.volume306en_US
bordeaux.hal.laboratoriesNutriNeurO (Laboratoire de Nutrition et Neurobiologie Intégrée) - UMR 1286en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINRAEen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDFondation FondaMentalen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
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