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The Role of MicroRNA and Microbiota in Depression and Anxiety
| dc.rights.license | open | en_US |
| dc.contributor.author | ROSA, Julia M. | |
| dc.contributor.author | FORMOLO, Douglas A. | |
| dc.contributor.author | JU, Jiasui | |
| hal.structure.identifier | Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB] | |
| dc.contributor.author | LEE, Thomas H. | |
| dc.contributor.author | YAU, Suk-Yu | |
| dc.date.accessioned | 2022-11-09T10:16:20Z | |
| dc.date.available | 2022-11-09T10:16:20Z | |
| dc.date.issued | 2022-03-01 | |
| dc.identifier.issn | 1662-5153 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/170239 | |
| dc.description.abstractEn | Depression and anxiety are devastating disorders. Understanding the mechanisms that underlie the development of depression and anxiety can provide new hints on novel treatments and preventive strategies. Here, we summarize the latest findings reporting the novel roles of gut microbiota and microRNAs (miRNAs) in the pathophysiology of depression and anxiety. The crosstalk between gut microbiota and the brain has been reported to contribute to these pathologies. It is currently known that some miRNAs can regulate bacterial growth and gene transcription while also modulate the gut microbiota composition, suggesting the importance of miRNAs in gut and brain health. Treatment and prevention strategies for neuropsychiatric diseases, such as physical exercise, diet, and probiotics, can modulate the gut microbiota composition and miRNAs expressions. Nonetheless, there are critical questions to be addressed to understand further the mechanisms involved in the interaction between the gut microbiota and miRNAs in the brain. This review summarizes the recent findings of the potential roles of microbiota and miRNA on the neuropathology of depression and anxiety, and its potential as treatment strategies. Copyright © 2022 Rosa, Formolo, Yu, Lee and Yau. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
| dc.subject.en | Microrna | |
| dc.subject.en | Microrna 122 5p | |
| dc.subject.en | Microrna 1298 5p | |
| dc.subject.en | Microrna 182 3p | |
| dc.subject.en | Microrna 182 5p | |
| dc.subject.en | Microrna 183 5p | |
| dc.subject.en | Microrna 184 3p | |
| dc.subject.en | Microrna 187 3p | |
| dc.subject.en | Microrna 190a 5p | |
| dc.subject.en | Microrna 204 5p | |
| dc.subject.en | Microrna 206 3p | |
| dc.subject.en | Microrna 211 5p | |
| dc.subject.en | Microrna 219a 2 3p | |
| dc.subject.en | Microrna 3095 3p | |
| dc.subject.en | Microrna 342 5p | |
| dc.subject.en | Microrna 344c 3p | |
| dc.subject.en | Microrna 3535 | |
| dc.subject.en | Microrna 363 5p | |
| dc.subject.en | Microrna 369 3p | |
| dc.subject.en | Microrna 369 5p | |
| dc.subject.en | Microrna 380 3p | |
| dc.subject.en | Microrna 421 3p | |
| dc.subject.en | Microrna 448 3p | |
| dc.subject.en | Microrna 485 3p | |
| dc.subject.en | Microrna 539 5p | |
| dc.subject.en | Microrna 673 3p | |
| dc.subject.en | Microrna 758 5p | |
| dc.subject.en | Microrna 760 3p | |
| dc.subject.en | Microrna 874 3p | |
| dc.subject.en | Microrna 92b 5p | |
| dc.subject.en | Unclassified Drug | |
| dc.subject.en | Amygdala | |
| dc.subject.en | Anterior Cingulate | |
| dc.subject.en | Anxiety Disorder | |
| dc.subject.en | Brain Nerve Cell | |
| dc.subject.en | Depression | |
| dc.subject.en | Gene Expression | |
| dc.subject.en | Hippocampus | |
| dc.subject.en | Human | |
| dc.subject.en | Intestine Flora | |
| dc.subject.en | Microbial Diversity | |
| dc.subject.en | Microflora | |
| dc.subject.en | Nonhuman | |
| dc.subject.en | Pathogenesis | |
| dc.subject.en | Physiological Stress | |
| dc.subject.en | Prefrontal Cortex | |
| dc.subject.en | Review | |
| dc.subject.en | Synapse | |
| dc.title.en | The Role of MicroRNA and Microbiota in Depression and Anxiety | |
| dc.title.alternative | Front Behav Neurosci. | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.3389/fnbeh.2022.828258 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC] | en_US |
| dc.identifier.pubmed | 35299696 | en_US |
| bordeaux.journal | Frontiers in Behavioral Neuroscience | en_US |
| bordeaux.volume | 16 | en_US |
| bordeaux.hal.laboratories | Neurocentre Magendie - U1215 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | Physiopathologie de l'équilibre énergétique et obésité | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.identifier.funderID | Hong Kong Polytechnic University | en_US |
| hal.identifier | hal-03845037 | |
| hal.version | 1 | |
| hal.date.transferred | 2022-11-09T10:16:29Z | |
| hal.export | true | |
| dc.rights.cc | CC BY | en_US |
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