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hal.structure.identifierBiothérapies des maladies génétiques et cancers
hal.structure.identifierCentre de Bioinformatique de Bordeaux [CBIB]
dc.contributor.authorSOUEIDAN, Hayssam
hal.structure.identifierCentre de Bioinformatique de Bordeaux [CBIB]
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
dc.contributor.authorSCHMITT, Louise-Amélie
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorCANDRESSE, Thierry
hal.structure.identifierCentre de Bioinformatique de Bordeaux [CBIB]
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
dc.contributor.authorNIKOLSKI, Macha
dc.date.issued2014-12-05
dc.identifier.issn1664-302X
dc.description.abstractEnCollectively, viruses have the greatest genetic diversity on Earth, occupy extremely varied niches and are likely able to infect all living organisms. Viral infections are an important issue for human health and cause considerable economic losses when agriculturally important crops or husbandry animals are infected. The advent of metagenomics has provided a precious tool to study viruses by sampling them in natural environments and identifying the genomic composition of a sample. However, reaching a clear recognition and taxonomic assignment of the identified viruses has been hampered by the computational difficulty of these problems. In this perspective paper we examine the trends in current research for the identification of viral sequences in a metagenomic sample, pinpoint the intrinsic computational difficulties for the identification of novel viral sequences within metagenomic samples, and suggest possible avenues to overcome them.
dc.language.isoen
dc.publisherFrontiers Media
dc.rights.urihttp://creativecommons.org/licenses/by/
dc.subject.enTaxonomic assignment
dc.subject.enhost-pathogen interactions
dc.subject.enNGS
dc.subject.envirome
dc.subject.enmicrobial metagenomics
dc.title.enFinding and identifying the viral needle in the metagenomic haystack: Trends and Challenges
dc.typeArticle de revue
dc.identifier.doi10.3389/fmicb.2014.00739
dc.subject.halInformatique [cs]/Bio-informatique [q-bio.QM]
dc.subject.halInformatique [cs]/Apprentissage [cs.LG]
dc.subject.halSciences du Vivant [q-bio]/Biodiversité/Systématique, phylogénie et taxonomie
bordeaux.journalFrontiers in Microbiology
bordeaux.page5:739
bordeaux.volume5
bordeaux.peerReviewedoui
hal.identifierhal-01100888
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-01100888v1
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