CARDINALE, Daniela; CARETTE, Noelle; MICHON, Thierry

doi:10.1016/j.tibtech.2012.04.001

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CARDINALE, Daniela
Biologie du fruit et pathologie [BFP]

CARETTE, Noelle
Biologie du fruit et pathologie [BFP]

MICHON, Thierry
Biologie du fruit et pathologie [BFP]

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Article de revue

Ce document a été publié dans

Trends in Biotechnology. 2012, vol. 30, n° 7, p. 369 - 376

Elsevier

Résumé en anglais

The cooperative organization of enzymes by cells is a key feature for the efficiency of living systems. In the field of nanotechnologies, effort currently aims at mimicking this natural organization. Nanoscale resolution and high-registration alignment are necessary to control enzyme distribution in nano-containers or on the surface of solid supports. Virus capsid self-assembly is driven by precise supramolecular combinations of protein monomers, which have made them attractive building blocks to engineer enzyme nano-carriers (ENCs). We discuss some examples of what in our opinion constitute the latest advances in the use of plant viruses, bacteriophages and virus-like particles (VLPs) as nano-scaffolds for enzyme selection, enzyme confinement and patterning, phage therapy, raw material processing, and single molecule enzyme kinetics studies.< Réduire

Mots clés

PEPTIDE FUSION LIBRARIES

PARTICLES

Mots clés en anglais

enzyme nano-carrier

virus-like particle

virus scaffold

bacteriophage

enzyme selection

BETA-LACTAMASE

PHAGE DISPLAY

SELECTION