Optical readout of gold nanoparticles-based DNA microarrays without silver enhancement
Langue
en
Article de revue
Ce document a été publié dans
Biophysical Journal. 2006-01-01, vol. 90, n° 1, p. L13
Biophysical Society
Résumé en anglais
We present a novel readout scheme for gold nanoparticle-based DNA microarrays relying on Laser Induced Scattering around a NanoAbsorber (LISNA). It provides direct counting of individual nanoparticles present on each array ...Lire la suite >
We present a novel readout scheme for gold nanoparticle-based DNA microarrays relying on Laser Induced Scattering around a NanoAbsorber (LISNA). It provides direct counting of individual nanoparticles present on each array spot and stable signals, without any silver enhancement. Given the detection of nanometer-sized particles, which minimize the steric hindrance, the linear dynamic range of the method is particularly large and well suited for microarray detection.< Réduire
Mots clés en italien
single particle
dna chips
Origine
Importé de halUnités de recherche