C3-triiodocyclotriveratrylene as a key intermediate to fluorescent probes: application to selective choline recognition
hal.structure.identifier | Institut des Sciences Moléculaires [ISM] | |
dc.contributor.author | PEYRARD, Lisa | |
hal.structure.identifier | Département de Chimie Moléculaire [DCM] | |
dc.contributor.author | CHIERICI, Sabine | |
hal.structure.identifier | Institut des Sciences Moléculaires [ISM] | |
dc.contributor.author | PINET, Sandra | |
hal.structure.identifier | Laboratoire Ondes et Matière d'Aquitaine [LOMA] | |
dc.contributor.author | BATAT, Pinar | |
hal.structure.identifier | Laboratoire Ondes et Matière d'Aquitaine [LOMA] | |
dc.contributor.author | JONUSAUSKAS, Gediminas | |
hal.structure.identifier | Institut des Sciences Moléculaires [ISM] | |
dc.contributor.author | PINAUD, Noël | |
hal.structure.identifier | Institut des Maladies Neurodégénératives [Bordeaux] [IMN] | |
dc.contributor.author | MEYRAND, Pierre | |
hal.structure.identifier | Institut des Sciences Moléculaires [ISM] | |
dc.contributor.author | GOSSE, Isabelle | |
dc.date.created | 2011-07-22 | |
dc.date.issued | 2011-12-21 | |
dc.identifier.issn | 1477-0520 | |
dc.description.abstractEn | A new strategy to obtain fluorescent cyclotriveratrylene (CTV) probes is proposed. The key intermediate, a triiodo CTV, is prepared in 3 steps with 47% overall yield. The whole synthesis requires only one purification step. The potential of this triiodo CTV as an intermediate is illustrated through the synthesis of a fluorescent phosphorylated probe that is able to bind choline and acetylcholine in pseudo-physiological conditions, with selectivity towards choline. As a consequence, this intermediate should allow us to rapidly form a library of probes in order to highlight the most promising ones. | |
dc.language.iso | en | |
dc.publisher | Royal Society of Chemistry | |
dc.title.en | C3-triiodocyclotriveratrylene as a key intermediate to fluorescent probes: application to selective choline recognition | |
dc.type | Article de revue | |
dc.identifier.doi | 10.1039/C1OB06231J | |
dc.subject.hal | Physique [physics]/Physique [physics]/Chimie-Physique [physics.chem-ph] | |
bordeaux.journal | Organic & Biomolecular Chemistry | |
bordeaux.page | 8489-8494 | |
bordeaux.volume | 9 | |
bordeaux.issue | 24 | |
bordeaux.peerReviewed | oui | |
hal.identifier | hal-00673589 | |
hal.version | 1 | |
hal.popular | non | |
hal.audience | Internationale | |
hal.origin.link | https://hal.archives-ouvertes.fr//hal-00673589v1 | |
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