Cyclo-(DfKRG) peptide grafting onto Ti–6Al–4V: physical characterization and interest towards human osteoprogenitor cells adhesion
Langue
en
Article de revue
Ce document a été publié dans
Biomaterials. 2004, vol. 25, n° 19, p. 4837-4846
Elsevier
Résumé en anglais
In the present paper, specific interest has been devoted to the design of new hybrid materials associating Ti–6Al–4V alloy and osteoprogenitor cells through the grafting of two RGD containing peptides displaying a different ...Lire la suite >
In the present paper, specific interest has been devoted to the design of new hybrid materials associating Ti–6Al–4V alloy and osteoprogenitor cells through the grafting of two RGD containing peptides displaying a different conformation (linear RGD and cyclo-DfKRG) onto titanium surface. Biomimetic modification was performed by means of a three-step reaction procedure: silanization with APTES, cross-linking with SMP and finally immobilization of peptides thanks to thiol bonding...< Réduire
Mots clés en italien
Biomimetic material
Titanium alloy
RGD peptide
Cell adhesion
Origine
Importé de halUnités de recherche