PRAKASAM, Mythili; SILVAIN, Jean-François; LARGETEAU, Alain

doi:10.3390/bioengineering8110170

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PRAKASAM, Mythili
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]

SILVAIN, Jean-François
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]

LARGETEAU, Alain
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]

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Bioengineering. 2021-11-01, vol. 8, n° 11, p. 170 (22 p.)

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Biomaterials and their clinical application have become well known in recent years and progress in their manufacturing processes are essential steps in their technological advancement. Great advances have been made in the field of biomaterials, including ceramics, glasses, polymers, composites, glass-ceramics and metal alloys. Dense and porous ceramics have been widely used for various biomedical applications. Current applications of bioceramics include bone grafts, spinal fusion, bone repairs, bone fillers, maxillofacial reconstruction, etc. One of the common impediments in the bioceramics and metallic porous implants for biomedical applications are their lack of mechanical strength. High-pressure processing can be a viable solution in obtaining porous biomaterials. Many properties such as mechanical properties, non-toxicity, surface modification, degradation rate, biocompatibility, corrosion rate and scaffold design are taken into consideration. The current review focuses on different manufacturing processes used for bioceramics, polymers and metals and their alloys in porous forms. Recent advances in the manufacturing technologies of porous ceramics by freeze isostatic pressure and hydrothermal processing are discussed in detail. Pressure as a parameter can be helpful in obtaining porous forms for biomaterials with increased mechanical strength.< Réduire

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bioceramics

metallic implants

biodegradable polymers

porous biomaterials

high pressure processing

freeze isostatic pressure

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Innovative high-pressure fabrication processes for porous biomaterials—A review

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