GEESI, Mohammed; RIADI, Yassine; KAIBA, Abdellah; IBNOUF, Elmutasim; ANOUAR, El Hassane; DEHBI, Oussama; LAZAR, Saïd; GUIONNEAU, Philippe

doi:10.1016/j.molstruc.2022.133425

Métadonnées

Afficher la notice complète

Licence d’utilisation du document

GEESI, Mohammed
Prince Sattam Bin Abdul-Aziz University [PSAU]

RIADI, Yassine
Prince Sattam Bin Abdul-Aziz University [PSAU]

KAIBA, Abdellah
Prince Sattam Bin Abdul-Aziz University [PSAU]

Langue

Article de revue

Ce document a été publié dans

Journal of Molecular Structure. 2022, vol. 1265, p. 133425

Elsevier

Résumé en anglais

The synthesis of a new 4-[2-(1-methyl-1H-imidazol-2-ylsulfanyl)-acetylamino]-benzenesulfonic acid from available reagents using an efficient strategy was reported, and its antimicrobial ability against bacterial strains was investigated. This new compound was characterised using a single crystal technique, which showed that the compound crystallised with a monoclinic system in a P21/c space group. Its unit-cell parameters were a = 17.0692 (2) Å, b = 5.0326 (3) Å, c = 17.2979 (4) Å, β = 106.596° (2) and Z = 4. Crystal packing was stabilised by hydrogen bonds, pi- stacking, Csingle bondH….pi and van der Waals interactions. The intermolecular interaction analysis of the crystal structure was affected by Hirschfeld surface analysis, and associated two-dimensional fingerprint plots were utilised. In addition, docking investigations of the biological activity of the synthesised compound was also performed.< Réduire

Mots clés en anglais

Synthesis

Docking

Antimicrobial activity

Crystal structure

Hirshfeld surface analysis

Métadonnées

Licence d’utilisation du document

Synthesis, antimicrobial evaluation, crystal structure, Hirschfeld surface analysis and docking studies of 4-[2-(1-methyl-1H-imidazol-2-ylsulfanyl)-acetylamino]-benzenesulfonic acid

Langue

Ce document a été publié dans

Résumé en anglais

Mots clés en anglais

DOI

Origine

Unités de recherche