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hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
hal.structure.identifierEllipse Pharmaceutical
hal.structure.identifierLaboratoire de Technologie Pharmaceutique Industrielle [LTIP]
dc.contributor.authorRIGALDIE, Yohan
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorLARGETEAU, Alain
hal.structure.identifierLaboratoire de Technologie Pharmaceutique Industrielle [LTIP]
dc.contributor.authorLEMAGNEN, Gilles
hal.structure.identifierLaboratoire de Technologie Pharmaceutique Industrielle [LTIP]
dc.contributor.authorLARROUTURE, Denis
hal.structure.identifierEllipse Pharmaceutical
dc.contributor.authorHALLER, R.
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorDEMAZEAU, Gérard
hal.structure.identifierLaboratoire de Technologie Pharmaceutique Industrielle [LTIP]
dc.contributor.authorGRISLAIN, Luc
dc.date.issued2002
dc.identifier.issn0895-7959
dc.description.abstractEnThe aim of this study was to investigate the use of HHP (High Hydrostatic Pressure) technology as a possible alternative method for decontamination and sterilization of sensitive drugs. We demonstrated the safety of HHP treatment on several sensitive biomolecules. A 10 min. HHP treatment inactivates totally pure suspensions of P. aeruginosa , C. albicans and spores of A. niger , but S. aureus needs a longer HHP duration treatment to be totally inactivated. Endospores appear to be more baroresistant.
dc.language.isoen
dc.publisherTaylor & Francis
dc.subject.enHigh Pressure
dc.subject.enPharmacy
dc.subject.enSterilization
dc.subject.enFragile Drugs
dc.subject.enPharmacopoeia Strains
dc.title.enSterilization of liquid and semi-solid pharmaceutical forms using high pressure technology
dc.typeArticle de revue
dc.identifier.doi10.1080/08957950212456
dc.subject.halChimie/Matériaux
bordeaux.journalHigh Pressure Research
bordeaux.page747-749
bordeaux.volume22
bordeaux.issue3-4
bordeaux.peerReviewedoui
hal.identifierhal-00715319
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-00715319v1
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