Sterilization of liquid and semi-solid pharmaceutical forms using high pressure technology
RIGALDIE, Yohan
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
Ellipse Pharmaceutical
Laboratoire de Technologie Pharmaceutique Industrielle [LTIP]
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Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
Ellipse Pharmaceutical
Laboratoire de Technologie Pharmaceutique Industrielle [LTIP]
RIGALDIE, Yohan
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
Ellipse Pharmaceutical
Laboratoire de Technologie Pharmaceutique Industrielle [LTIP]
< Reduce
Institut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
Ellipse Pharmaceutical
Laboratoire de Technologie Pharmaceutique Industrielle [LTIP]
Language
en
Article de revue
This item was published in
High Pressure Research. 2002, vol. 22, n° 3-4, p. 747-749
Taylor & Francis
English Abstract
The aim of this study was to investigate the use of HHP (High Hydrostatic Pressure) technology as a possible alternative method for decontamination and sterilization of sensitive drugs. We demonstrated the safety of HHP ...Read more >
The aim of this study was to investigate the use of HHP (High Hydrostatic Pressure) technology as a possible alternative method for decontamination and sterilization of sensitive drugs. We demonstrated the safety of HHP treatment on several sensitive biomolecules. A 10 min. HHP treatment inactivates totally pure suspensions of P. aeruginosa , C. albicans and spores of A. niger , but S. aureus needs a longer HHP duration treatment to be totally inactivated. Endospores appear to be more baroresistant.Read less <
English Keywords
High Pressure
Pharmacy
Sterilization
Fragile Drugs
Pharmacopoeia Strains
Origin
Hal imported