Use of jump-tests for the characterization of the viscoplastic behavior of pharmaceutical powders during compaction
| dc.rights.license | open | en_US |
| hal.structure.identifier | Institut de Mécanique et d'Ingénierie [I2M] | |
| dc.contributor.author | DESBOIS, Léo | |
| hal.structure.identifier | Institut de Mécanique et d'Ingénierie [I2M] | |
| dc.contributor.author | TCHORELOFF, Pierre
IDREF: 069233624 | |
| hal.structure.identifier | Institut de Mécanique et d'Ingénierie [I2M] | |
| dc.contributor.author | MAZEL, Vincent
IDREF: 113057954 | |
| dc.date.accessioned | 2022-09-14T09:11:14Z | |
| dc.date.available | 2022-09-14T09:11:14Z | |
| dc.date.issued | 2022-05 | |
| dc.identifier.issn | 0032-5910 | en_US |
| dc.identifier.uri | oai:crossref.org:10.1016/j.powtec.2022.117406 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/144621 | |
| dc.description.abstractEn | Strain rate sensitivity (SRS) corresponds to the influence of the compaction kinematic on the powder behavior during compaction and on the final tablet properties. Several physical phenomena can explain the SRS like viscoelasticity or viscoplasticity. This work focuses on the case of viscoplasticity, especially by choosing products that are known to present little viscoelasticity. First, monotonic compression at different speed were performed and demonstrated that viscoplasticity was not constant during the whole compaction. Then, Jump tests showed the existence of transient phenomena during speed changed that are similar to phenomena described in the literature as dynamic strain aging. Introduction of long dwell-times during jump tests also indicated that all the products presented a stress relaxation even at slow speed. This was confirmed on long relaxation experiments (10h). As a consequence, for viscoplasticity, even compactions performed at very slow speed must be considered as dynamic. | |
| dc.language.iso | EN | en_US |
| dc.source | crossref | |
| dc.subject.en | Viscoplasticity | |
| dc.subject.en | Compaction | |
| dc.subject.en | Speed | |
| dc.subject.en | Strain rate sensitivity | |
| dc.subject.en | Mechanical behavior | |
| dc.subject.en | Tablet | |
| dc.title.en | Use of jump-tests for the characterization of the viscoplastic behavior of pharmaceutical powders during compaction | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1016/j.powtec.2022.117406 | en_US |
| dc.subject.hal | Sciences de l'ingénieur [physics]/Matériaux | |
| bordeaux.journal | Powder Technology | en_US |
| bordeaux.page | 117406 | en_US |
| bordeaux.volume | 404 | en_US |
| bordeaux.hal.laboratories | Institut de Mécanique et d’Ingénierie de Bordeaux (I2M) - UMR 5295 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | Bordeaux INP | en_US |
| bordeaux.institution | CNRS | en_US |
| bordeaux.institution | INRAE | en_US |
| bordeaux.institution | Arts et Métiers | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | dissemin | |
| hal.identifier | hal-03782120 | |
| hal.version | 1 | |
| hal.date.transferred | 2022-09-21T06:57:52Z | |
| hal.export | true | |
| workflow.import.source | dissemin | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Powder%20Technology&rft.date=2022-05&rft.volume=404&rft.spage=117406&rft.epage=117406&rft.eissn=0032-5910&rft.issn=0032-5910&rft.au=DESBOIS,%20L%C3%A9o&TCHORELOFF,%20Pierre&MAZEL,%20Vincent&rft.genre=article |
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