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dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorCHAMBERLAIN, Jonviea D.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorROUANET, Anais
IDREF: 198306717
dc.contributor.authorDUBOIS, Bruno
dc.contributor.authorPASQUIER, Florence
dc.contributor.authorHANON, Olivier
dc.contributor.authorGABELLE, Audrey
dc.contributor.authorCECCALDI, Mathieu
dc.contributor.authorKROLAK-SALMON, Pierre
dc.contributor.authorBEJOT, Yannick
dc.contributor.authorGODEFROY, Olivier
dc.contributor.authorWALLON, David
dc.contributor.authorGENTRIC, Armelle
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorCHENE, Genevieve
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDUFOUIL, Carole
dc.date.accessioned2022-06-15T14:12:29Z
dc.date.available2022-06-15T14:12:29Z
dc.date.issued2021-09
dc.identifier.issn2352-8729en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/140236
dc.description.abstractEnIntroductionStudies on the association of cancer and risk of dementia are inconclusive due to result heterogeneity and concerns of survivor bias and unmeasured confounding.MethodsThis study uses data from the Memento cohort, a French multicenter cohort following persons with either mild or isolated cognitive complaints for a median of 5 years. Illness‐death models (IDMs) were used to estimate transition‐specific hazard ratios (HRs) and 95% confidence intervals (CIs) for incident cancer in relation to dementia from time since study entry.ResultsThe analytical sample (N = 2258) excluded 65 individuals without follow‐up information. At the end of follow‐up, 286 individuals were diagnosed with dementia, 166 with incident cancer, and 95 died. Incident cancer was associated with a reduced risk of dementia (HR = 0.58, 95% CI = 0.35‐0.97), with a corresponding E‐value of 2.84 (lower CI = 1.21).DiscussionThis study supports a protective relationship between incident cancer and dementia, encouraging further investigations to understand potential underlying mechanisms.
dc.language.isoENen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subject.enillness-death model
dc.subject.enselection bias
dc.subject.enAlzheimer's disease
dc.subject.encancer
dc.subject.endementia
dc.subject.enepidemiology
dc.title.enInvestigating the association between cancer and the risk of dementia: Results from the Memento cohort
dc.typeArticle de revueen_US
dc.identifier.doi10.1002/alz.12308en_US
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]en_US
dc.identifier.pubmed33656287en_US
bordeaux.journalAlzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoringen_US
bordeaux.page1415-1421en_US
bordeaux.volume17en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue9en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamVINTAGEen_US
bordeaux.teamMORPH3Eusen_US
bordeaux.teamMEMENTOen_US
bordeaux.teamBIOSTAT_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcehal
hal.identifierhal-03159297
hal.version1
hal.exportfalse
workflow.import.sourcehal
dc.rights.ccCC BY-NC-NDen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Alzheimer's%20&%20Dementia:%20Diagnosis,%20Assessment%20&%20Disease%20Monitoring&rft.date=2021-09&rft.volume=17&rft.issue=9&rft.spage=1415-1421&rft.epage=1415-1421&rft.eissn=2352-8729&rft.issn=2352-8729&rft.au=CHAMBERLAIN,%20Jonviea%20D.&ROUANET,%20Anais&DUBOIS,%20Bruno&PASQUIER,%20Florence&HANON,%20Olivier&rft.genre=article


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