Coupling of Geant4-DNA physics models into the GATE Monte Carlo platform: Evaluation of radiation-induced damage for clinical and preclinical radiation therapy beams
hal.structure.identifier | Laboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC] | |
dc.contributor.author | PHAM, T.Q. | |
hal.structure.identifier | Laboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC] | |
dc.contributor.author | ANNE, A. | |
hal.structure.identifier | Laboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC] | |
dc.contributor.author | BONY, M. | |
hal.structure.identifier | Laboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC] | |
dc.contributor.author | DELAGE, E. | |
hal.structure.identifier | Laboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC] | |
hal.structure.identifier | Centre Jean Perrin [Clermont-Ferrand] [UNICANCER/CJP] | |
dc.contributor.author | DONNARIEIX, D. | |
hal.structure.identifier | Laboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC] | |
dc.contributor.author | DUFAURE, A. | |
hal.structure.identifier | Laboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC] | |
dc.contributor.author | GAUTIER, M. | |
hal.structure.identifier | Proton Therapy Center | |
dc.contributor.author | LEE, S.B. | |
hal.structure.identifier | Laboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC] | |
dc.contributor.author | MICHEAU, P. | |
hal.structure.identifier | Laboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC] | |
dc.contributor.author | MONTAROU, G. | |
hal.structure.identifier | Laboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC] | |
dc.contributor.author | PERROT, Y. | |
hal.structure.identifier | Proton Therapy Center | |
dc.contributor.author | SHIN, J.I. | |
hal.structure.identifier | Centre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG] | |
dc.contributor.author | INCERTI, S. | |
hal.structure.identifier | Laboratoire de Physique Corpusculaire - Clermont-Ferrand [LPC] | |
dc.contributor.author | MAIGNE, L. | |
dc.date.issued | 2015 | |
dc.identifier.issn | 0168-583X | |
dc.description.abstractEn | The GATE Monte Carlo simulation platform based on the Geant4 toolkit is in constant improvement for dosimetric calculations. In this paper, we present the integration of Geant4-DNA processes into the GATE 7.0 platform in the objective to perform multi-scale simulations (from macroscopic to nanometer scale). We simulated three types of clinical and preclinical beams: a 6 MeV electron clinical beam, a X-ray irradiator beam and a clinical proton beam for which we validated depth dose distributions against measurements in water. Frequencies of energy depositions and DNA damage were evaluated using a specific algorithm in charge of allocating energy depositions to atoms constituting DNA molecules represented by their PDB (Protein Data Bank) description. | |
dc.language.iso | en | |
dc.publisher | Elsevier | |
dc.subject.en | Nanodosimetry | |
dc.subject.en | Monte Carlo | |
dc.subject.en | GATE | |
dc.subject.en | Geant4-DNA | |
dc.title.en | Coupling of Geant4-DNA physics models into the GATE Monte Carlo platform: Evaluation of radiation-induced damage for clinical and preclinical radiation therapy beams | |
dc.type | Article de revue | |
dc.identifier.doi | 10.1016/j.nimb.2015.04.024 | |
dc.subject.hal | Informatique [cs]/Modélisation et simulation | |
bordeaux.journal | Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms | |
bordeaux.page | 46–55 | |
bordeaux.volume | 353 | |
bordeaux.peerReviewed | oui | |
hal.identifier | hal-01288784 | |
hal.version | 1 | |
hal.popular | non | |
hal.audience | Internationale | |
hal.origin.link | https://hal.archives-ouvertes.fr//hal-01288784v1 | |
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