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dc.contributor.authorTRAN, H.N.
dc.contributor.authorKARAMITROS, M.
dc.contributor.authorIVANCHENKO, V.N.
dc.contributor.authorGUATELLI, S.
dc.contributor.authorMCKINNON, S.
hal.structure.identifierKEK [High energy accelerator research organization]
dc.contributor.authorMURAKAMI, K.
hal.structure.identifierKEK [High energy accelerator research organization]
dc.contributor.authorSASAKI, T.
hal.structure.identifierKEK [High energy accelerator research organization]
dc.contributor.authorOKADA, S.
hal.structure.identifierCentre de Recherches en Cancérologie de Toulouse [CRCT]
dc.contributor.authorBORDAGE, Marie-Claude
hal.structure.identifierDepartment of Physics, Faculty of Sciences
dc.contributor.authorFRANCIS, Z.
hal.structure.identifierInstitut Pluridisciplinaire Hubert Curien [IPHC]
dc.contributor.authorEL BITAR, Z.
dc.contributor.authorBERNAL, M.A.
dc.contributor.authorSHIN, J.I.
dc.contributor.authorLEE, S.
dc.contributor.authorBARBERET, Ph.
dc.contributor.authorTRAN, T.T.
dc.contributor.authorBROWN, J.M.C.
dc.contributor.authorNHAN HAO, T.V.
hal.structure.identifierCentre d'Etudes Nucléaires de Bordeaux Gradignan [CENBG]
dc.contributor.authorINCERTI, S.
dc.date.issued2016
dc.identifier.issn0168-583X
dc.description.abstractEnGold nanoparticles have been reported as a possible radio-sensitizer agent in radiation therapy due totheir ability to increase energy deposition and subsequent direct damage to cells and DNA within theirlocal vicinity. Moreover, this increase in energy deposition also results in an increase of the radiochemicalyields. In this work we present, for the first time, an in silico investigation, based on the general purposeMonte Carlo simulation toolkit Geant4, into energy deposition and radical species production around aspherical gold nanoparticle 50 nm in diameter via proton irradiation. Simulations were preformed forincident proton energies ranging from 2 to 170 MeV, which are of interest for clinical proton therapy.
dc.language.isoen
dc.publisherElsevier
dc.subject.enGeant4-DNA
dc.subject.enNanoparticle
dc.subject.enRadiolysis
dc.subject.enProton beam
dc.subject.enRadiation therapy
dc.title.enGeant4 Monte Carlo simulation of absorbed dose and radiolysis yields enhancement from a gold nanoparticle under MeV proton irradiation
dc.typeArticle de revue
dc.identifier.doi10.1016/j.nimb.2016.01.017
dc.subject.halPhysique [physics]
bordeaux.journalNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
bordeaux.page126 - 139
bordeaux.volume373
bordeaux.peerReviewedoui
hal.identifierhal-01401966
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-01401966v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nuclear%20Instruments%20and%20Methods%20in%20Physics%20Research%20Section%20B:%20Beam%20Interactions%20with%20Materials%20and%20Atoms&rft.date=2016&rft.volume=373&rft.spage=126%20-%20139&rft.epage=126%20-%20139&rft.eissn=0168-583X&rft.issn=0168-583X&rft.au=TRAN,%20H.N.&KARAMITROS,%20M.&IVANCHENKO,%20V.N.&GUATELLI,%20S.&MCKINNON,%20S.&rft.genre=article


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