Comparison of Simoa™ and Ella™ to assess serum neurofilament-light chain in multiple sclerosis
| dc.rights.license | open | en_US |
| dc.contributor.author | GAUTHIER, Audrey | |
| dc.contributor.author | VIEL, Sebastien | |
| dc.contributor.author | PERRET, Magali | |
| dc.contributor.author | BROCARD, Guillaume | |
| dc.contributor.author | CASEY, Romain | |
| dc.contributor.author | LOMBARD, Christine | |
| dc.contributor.author | LAURENT-CHABALIER, Sabine | |
| dc.contributor.author | DEBOUVERIE, Marc | |
| dc.contributor.author | EDAN, Gilles | |
| dc.contributor.author | VUKUSIC, Sandra | |
| dc.contributor.author | LEBRUN-FRENAY, Christine | |
| dc.contributor.author | DE SEZE, Jerome | |
| dc.contributor.author | LAPLAUD, David-Axel | |
| dc.contributor.author | CASTELNOVO, Giovanni | |
| dc.contributor.author | GOUT, Olivier | |
| hal.structure.identifier | Service de neurologie [Bordeaux] | |
| hal.structure.identifier | Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB] | |
| dc.contributor.author | RUET, Aurelie | |
| dc.contributor.author | MOREAU, Thibault | |
| dc.contributor.author | CASEZ, Olivier | |
| dc.contributor.author | CLAVELOU, Pierre | |
| dc.contributor.author | BERGER, Eric | |
| dc.contributor.author | ZEPHIR, Helene | |
| dc.contributor.author | TROUILLET-ASSANT, Sophie | |
| dc.contributor.author | THOUVENOT, Eric | |
| dc.date.accessioned | 2022-02-18T15:31:06Z | |
| dc.date.available | 2022-02-18T15:31:06Z | |
| dc.date.issued | 2021-05 | |
| dc.identifier.issn | 2328-9503 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/128748 | |
| dc.description.abstractEn | We compared SimoaTM and EllaTM immunoassays to assess serum neurofilament-light chain levels in 203 multiple sclerosis patients from the OFSEP HD study. There was a strong correlation (ρ = 0.86, p < 0.0001) between both platforms. The EllaTM instrument overestimated values by 17%, but as the data were linear (p = 0.57), it was possible to apply a correction factor to EllaTM results. As for SimoaTM, serum neurofilament-light chain levels measured by EllaTM were correlated with age and EDSS and were significantly higher in active multiple sclerosis, suggesting that these assays are equivalent and can be used in routine clinical practice. | |
| dc.description.sponsorship | Observatoire Français de la Sclérose en Plaques - ANR-10-COHO-0002 | en_US |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/2.0/us/ | * |
| dc.title.en | Comparison of Simoa™ and Ella™ to assess serum neurofilament-light chain in multiple sclerosis | |
| dc.title.alternative | Ann Clin Transl Neurol | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1002/acn3.51355 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC] | en_US |
| dc.identifier.pubmed | 33830650 | en_US |
| bordeaux.journal | Annals of Clinical and Translational Neurology | en_US |
| bordeaux.page | 1141-1150 | en_US |
| bordeaux.volume | 8 | en_US |
| bordeaux.hal.laboratories | Neurocentre Magendie - UMR-S 1215 | en_US |
| bordeaux.issue | 5 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.identifier.funderID | Agence Nationale de la Recherche | en_US |
| hal.export | false | |
| dc.rights.cc | CC BY | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Annals%20of%20Clinical%20and%20Translational%20Neurology&rft.date=2021-05&rft.volume=8&rft.issue=5&rft.spage=1141-1150&rft.epage=1141-1150&rft.eissn=2328-9503&rft.issn=2328-9503&rft.au=GAUTHIER,%20Audrey&VIEL,%20Sebastien&PERRET,%20Magali&BROCARD,%20Guillaume&CASEY,%20Romain&rft.genre=article |
