Incidence of lung and HPV-associated malignancies in HIV-infected patients
| dc.rights.license | open | en_US |
| dc.contributor.author | CHAUSSADE, Helene | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | LE-MAREC, Fabien | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | COUREAU, Gaelle | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | LELEUX, Olivier | |
| dc.contributor.author | NEAU, Didier | |
| hal.structure.identifier | Immunology from Concept and Experiments to Translation = Immunologie Conceptuelle, Expérimentale et Translationnelle [ImmunoConcept] | |
| dc.contributor.author | LAZARO, Estibaliz | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | AMADEO, Brice | |
| hal.structure.identifier | Immunology from Concept and Experiments to Translation = Immunologie Conceptuelle, Expérimentale et Translationnelle [ImmunoConcept] | |
| dc.contributor.author | DUFFAU, Pierre | |
| dc.contributor.author | FERRAND, Helene | |
| dc.contributor.author | COURTAULT, Carine | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | FOUCAN, Anne Sophie | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | WITTKOP, Linda | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | BONNET, Fabrice | |
| dc.date.accessioned | 2022-01-20T10:22:35Z | |
| dc.date.available | 2022-01-20T10:22:35Z | |
| dc.date.issued | 2021-12-17 | |
| dc.identifier.issn | 1473-5571 (Electronic) 0269-9370 (Linking) | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/124448 | |
| dc.description.abstractEn | OBJECTIVE: Cancers represent one of the leading cause of mortality/morbidity in patients living with HIV (PLHIV) in industrialized countries. The objective of our study was to compare incidence of lung and HPV-related cancers among PLHIV with general population over the 2010-2017 period.Design: Prospective and multicenter cohort study. METHODS: The study included patients with lung and HPV-related cancers from the ANRS CO3 Aquitaine cohort (PLHIV) and the general population-based cancer registry in Gironde area. We calculated incidence rates (IR) for 100,000 Person Year (PY) and Incidence Rate Ratios (IRR). RESULTS: Among the 3,572 PLHIV, 70 cancers were diagnosed in 68 patients including 35 lung and 35 HPV-related cancers (18 oropharyngeal, 11 anal, 6 cervix). IR of lung and HPV-related-cancers were 311.1 in PLHIV and 209.8 in general population for 100,000 PY, respectively. IRR were significantly increased in PLHIV for lung 1.8 [1.4; 2.2] and HPV-related cancer 1.3 [1.0; 1.6] and particularly high for patients between 40-49 years-old (IRR 4.4 [2.3; 8.4] for lung cancer and 3.7 [2.1; 6.5] for HPV-related cancer). CONCLUSIONS: We emphasized the persistent high risk of lung and HPV-related cancer despite advent of antiretroviral therapies, particularly in the age strata of 40-49 years. Screening procedures should take into account this finding. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | Anus neoplasms | |
| dc.subject.en | Cancer HPV | |
| dc.subject.en | HIV-1 | |
| dc.subject.en | Lung cancer | |
| dc.subject.en | Oropharyngeal neoplasms | |
| dc.subject.en | Uterine cervical neoplasms | |
| dc.title.en | Incidence of lung and HPV-associated malignancies in HIV-infected patients | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1097/QAD.0000000000003152 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 34923517 | en_US |
| bordeaux.journal | AIDS. Official journal of the international AIDS Society | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.institution | CNRS | |
| bordeaux.team | EPICENE | en_US |
| bordeaux.team | EPICENE_BPH | |
| bordeaux.team | MORPH3Eus | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.export | false | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=AIDS.%20Official%20journal%20of%20the%20international%20AIDS%20Society&rft.date=2021-12-17&rft.eissn=1473-5571%20(Electronic)%200269-9370%20(Linking)&rft.issn=1473-5571%20(Electronic)%200269-9370%20(Linking)&rft.au=CHAUSSADE,%20Helene&LE-MAREC,%20Fabien&COUREAU,%20Gaelle&LELEUX,%20Olivier&NEAU,%20Didier&rft.genre=article |
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