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Neural correlates of episodic memory in the Memento cohort

dc.rights.licenseopenen_US
dc.contributor.authorEPELBAUM, S.
dc.contributor.authorBOUTELOUP, V.
dc.contributor.authorMANGIN, J. F.
dc.contributor.authorLA CORTE, V.
dc.contributor.authorMIGLIACCIO, R.
dc.contributor.authorBERTIN, H.
dc.contributor.authorHABERT, M. O.
dc.contributor.authorFISCHER, C.
dc.contributor.authorAZOUANI, C.
dc.contributor.authorFILLON, L.
dc.contributor.authorCHUPIN, M.
dc.contributor.authorVELLAS, B.
dc.contributor.authorPASQUIER, F.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDARTIGUES, Jean-Francois
dc.contributor.authorBLANC, F.
dc.contributor.authorGABELLE, A.
dc.contributor.authorCECCALDI, M.
dc.contributor.authorKROLAK-SALMON, P.
dc.contributor.authorHUGON, J.
dc.contributor.authorHANON, O.
dc.contributor.authorROUAUD, O.
dc.contributor.authorDAVID, R.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorCHENE, Geneviève
dc.contributor.authorDUBOIS, B.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDUFOUIL, Carole
dc.date.accessioned2020-11-09T14:28:50Z
dc.date.available2020-11-09T14:28:50Z
dc.date.issued2018-05-22
dc.identifier.issn2352-8737en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/12164
dc.description.abstractEnIntroduction: The free and cued selective reminding test is used to identify memory deficits in mild cognitive impairment and demented patients. It allows assessing three processes: encoding, storage, and recollection of verbal episodic memory. Methods: We investigated the neural correlates of these three memory processes in a large cohort study. The Memento cohort enrolled 2323 outpatients presenting either with subjective cognitive decline or mild cognitive impairment who underwent cognitive, structural MRI and, for a subset, fluorodeoxyglucose-positron emission tomography evaluations. Results: Encoding was associated with a network including parietal and temporal cortices; storage was mainly associated with entorhinal and parahippocampal regions, bilaterally; retrieval was associated with a widespread network encompassing frontal regions. Discussion: The neural correlates of episodic memory processes can be assessed in large and standardized cohorts of patients at risk for Alzheimer's disease. Their relation to pathophysiological markers of Alzheimer's disease remains to be studied.
dc.language.isoENen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subject.enSEPIA
dc.subject.enCIC1401
dc.subject.enVINTAGE
dc.title.enNeural correlates of episodic memory in the Memento cohort
dc.title.alternativeAlzheimers Dementen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.trci.2018.03.010en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed29955665en_US
bordeaux.journalAlzheimer's & dementia (New York, N. Y.)en_US
bordeaux.page224-233en_US
bordeaux.volume4en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - U1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.teamSEPIAen_US
bordeaux.teamCIC1401en_US
bordeaux.teamVINTAGEen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
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