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dc.rights.licenseopenen_US
dc.contributor.authorTEBEKA, Sarah
dc.contributor.authorGODIN, Ophelia
dc.contributor.authorMAZER, Nicolas
dc.contributor.authorBELLIVIER, Frank
dc.contributor.authorCOURTET, Philippe
dc.contributor.authorETAIN, Bruno
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorGARD, Sebastien
dc.contributor.authorLEBOYER, Marion
dc.contributor.authorLLORCA, Pierre-Michel
dc.contributor.authorLOFTUS, Josephine
dc.contributor.authorOLIE, Emilie
dc.contributor.authorPASSERIEUX, Christine
dc.contributor.authorPOLOSAN, Mircea
dc.contributor.authorSCHWAN, Raymund
dc.contributor.authorBELZEAUX, Raoul
dc.contributor.authorDUBERTRET, Caroline
dc.date.accessioned2021-10-19T15:40:15Z
dc.date.available2021-10-19T15:40:15Z
dc.date.issued2021
dc.identifier.issn0278-5846en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/112820
dc.description.abstractEnBackground: Postpartum period is associated with an increased risk of bipolar disorder diagnosis and relapse, mainly major depressive episode. Onset during this period might be associated with specific characteristics. Aim: To compare the socio-demographic and clinical characteristics of parous women presenting with bipolar disorder and an index depressive episode occurring during or outside the postpartum period. Methods: Using the multicenter cohort FACE-BD (FondaMental Academic Centers of Expertise for Bipolar Disorders), we considered all women who started their BD with a major depressive episode and have at least one child. We compared two groups depending on the onset: in or outside the postpartum period. Results: Among the 759 women who started BD with a major depressive episode, 93 (12.2%) had a postpartum onset, and 666 (87.8%) had not. Women who started BD in the postpartum period with a major depressive episode have a more stable family life, more children, an older age at onset, more Bipolar 2 disorder, less history of suicide attempts, less depressive episodes and more mood stabilizer treatments as compared to those who started with a major depressive episode outside the postpartum period. The multivariable logistic regression showed that women with an onset in the postpartum period had significantly more children, less lifetime depressive episodes and a lower rate of history of suicide attempts as compared to women with an onset outside the postpartum period. Discussion: Our results suggest that women starting their BD with postpartum depression have a more favorable course of BD, especially less history of suicide attempt and less lifetime depressive episodes.
dc.description.sponsorshipSorbonne Universités à Paris pour l'Enseignement et la Recherche - ANR-11-IDEX-0004en_US
dc.description.sponsorshipFondaMental-Cohortes - ANR-10-COHO-0010en_US
dc.language.isoENen_US
dc.title.enClinical characteristics of bipolar disorders with postpartum depressive onset
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.pnpbp.2020.110225en_US
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]en_US
dc.identifier.pubmed33347983en_US
bordeaux.journalProgress in Neuro-Psychopharmacology and Biological Psychiatryen_US
bordeaux.volume107en_US
bordeaux.hal.laboratoriesNutriNeurO (Laboratoire de Nutrition et Neurobiologie Intégrée) - UMR 1286en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINRAEen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDFondation FondaMentalen_US
bordeaux.identifier.funderIDInstitut National de la Santé et de la Recherche Médicaleen_US
bordeaux.identifier.funderIDAssistance Publique - Hôpitaux de Parisen_US
hal.identifierhal-03411858
hal.version1
hal.date.transferred2021-11-02T14:47:25Z
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
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