dc.rights.license | open | en_US |
hal.structure.identifier | Institut des Maladies Neurodégénératives [Bordeaux] [IMN] | |
dc.contributor.author | CREMONA, Sandrine | |
hal.structure.identifier | Institut des Maladies Neurodégénératives [Bordeaux] [IMN] | |
dc.contributor.author | ZAGO, Laure | |
hal.structure.identifier | Institut des Maladies Neurodégénératives [Bordeaux] [IMN] | |
dc.contributor.author | MELLET, Emmanuel | |
hal.structure.identifier | Institut des Maladies Neurodégénératives [Bordeaux] [IMN] | |
dc.contributor.author | PETIT, Laurent | |
hal.structure.identifier | Institut des Maladies Neurodégénératives [Bordeaux] [IMN] | |
dc.contributor.author | LAURENT, Alexandre | |
hal.structure.identifier | Institut des Maladies Neurodégénératives [Bordeaux] [IMN] | |
dc.contributor.author | PEPE, Antonietta | |
hal.structure.identifier | Institut des Maladies Neurodégénératives [Bordeaux] [IMN] | |
dc.contributor.author | TSUCHIDA, Ami | |
hal.structure.identifier | Institut des Maladies Neurodégénératives [Bordeaux] [IMN] | |
dc.contributor.author | BEGUEDOU, Naka | |
hal.structure.identifier | Institut des Maladies Neurodégénératives [Bordeaux] [IMN] | |
dc.contributor.author | JOLIOT, Marc | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | TZOURIO, Christophe | |
hal.structure.identifier | Institut des Maladies Neurodégénératives [Bordeaux] [IMN] | |
dc.contributor.author | MAZOYER, Bernard | |
hal.structure.identifier | Institut des Maladies Neurodégénératives [Bordeaux] [IMN] | |
dc.contributor.author | CRIVELLO, Fabrice | |
dc.date.accessioned | 2021-10-01T09:54:46Z | |
dc.date.available | 2021-10-01T09:54:46Z | |
dc.date.issued | 2021-08-28 | |
dc.identifier.issn | 1065-9471 | en_US |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/112511 | |
dc.description.abstractEn | The relationship between hippocampal subfield volumetry and verbal list-learning test outcomes have mostly been studied in clinical and elderly populations, and remain controversial. For the first time, we characterized a relationship between verbal list-learning test outcomes and hippocampal subfield volumetry on two large separate datasets of 447 and 1,442 healthy young and middle-aged adults, and explored the processes that could explain this relationship. We observed a replicable positive linear correlation between verbal list-learning test free recall scores and CA1 volume, specific to verbal list learning as demonstrated by the hippocampal subfield volumetry independence from verbal intelligence. Learning meaningless items was also positively correlated with CA1 volume, pointing to the role of the test design rather than word meaning. Accordingly, we found that association-based mnemonics mediated the relationship between verbal list-learning test outcomes and CA1 volume. This mediation suggests that integrating items into associative representations during verbal list-learning tests explains CA1 volume variations: this new explanation is consistent with the associative functions of the human CA1. | |
dc.description.sponsorship | Multi-level Integrative Analysis of Brain Lateralization for Language | en_US |
dc.description.sponsorship | Initiative d'excellence de l'Université de Bordeaux - ANR-10-IDEX-0003 | en_US |
dc.description.sponsorship | Translational Research and Advanced Imaging Laboratory - ANR-10-LABX-0057 | en_US |
dc.language.iso | EN | en_US |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/us/ | * |
dc.subject.en | Association-based mnemonics | |
dc.subject.en | Healthy young adults | |
dc.subject.en | Hippocampal subfields | |
dc.subject.en | Reliability | |
dc.subject.en | Structural MRI | |
dc.subject.en | Verbal list-learning | |
dc.title.en | Novel characterization of the relationship between verbal list-learning outcomes and hippocampal subfields in healthy adults | |
dc.type | Article de revue | en_US |
dc.identifier.doi | 10.1002/hbm.25614 | en_US |
dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
dc.identifier.pubmed | 34453474 | en_US |
bordeaux.journal | Human Brain Mapping | en_US |
bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
bordeaux.institution | Université de Bordeaux | en_US |
bordeaux.institution | INSERM | en_US |
bordeaux.team | HEALTHY_BPH | |
bordeaux.peerReviewed | oui | en_US |
bordeaux.inpress | non | en_US |
bordeaux.identifier.funderID | Conseil Régional Aquitaine | en_US |
bordeaux.identifier.funderID | Fondation pour la Recherche Médicale | en_US |
hal.export | false | |
dc.rights.cc | Pas de Licence CC | en_US |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Human%20Brain%20Mapping&rft.date=2021-08-28&rft.eissn=1065-9471&rft.issn=1065-9471&rft.au=CREMONA,%20Sandrine&ZAGO,%20Laure&MELLET,%20Emmanuel&PETIT,%20Laurent&LAURENT,%20Alexandre&rft.genre=article | |