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Novel polycarboxylate porphyrins: Synthesis, characterization, photophysical properties and preliminary antimicrobial study against Gram-positive bacteria

dc.contributor.authorJIBLAOUI, Ahmad
dc.contributor.authorLEROY-LHEZ, Stephanie
dc.contributor.authorOUK, Tan-Sothea
dc.contributor.authorGRENIER, Karine
dc.contributor.authorSOL, Vincent
dc.date.accessioned2020-09-03T08:02:08Z
dc.date.available2020-09-03T08:02:08Z
dc.date.issued2015
dc.identifier.issn0960-894X
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/10972
dc.description.abstractEnWe describe the synthesis, characterization and photophysical properties of two new polycarboxylic photosensitizers. Owing to their structural design, these two compounds show water solubilities larger than natural carboxylic photosensitizers (e.g., protoporphyrin IX, hematoporphyrin, etc.) and also good singlet oxygen quantum yields. These compounds were tested as photo-antimicrobial agents against Staphylococcus aureus and Bacillus cereus strains. Results reveal that their photocytotoxicities are strongly dependent on their amphiphilic character and more precisely the number and position of the carboxylic acid and mesityl substituents. (C) 2014 Elsevier Ltd. All rights reserved.
dc.language.isoen
dc.title.enNovel polycarboxylate porphyrins: Synthesis, characterization, photophysical properties and preliminary antimicrobial study against Gram-positive bacteria
dc.typeArticle de revue
dc.identifier.doi10.1016/j.bmcl.2014.11.033
dc.subject.halChimie/Matériaux
bordeaux.journalBioorganic & Medicinal Chemistry Letters
bordeaux.page355-362
bordeaux.volume25
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN) - UMR 5248*
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN, UMR 5248)
bordeaux.issue2
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Bioorganic%20&%20Medicinal%20Chemistry%20Letters&rft.date=2015&rft.volume=25&rft.issue=2&rft.spage=355-362&rft.epage=355-362&rft.eissn=0960-894X&rft.issn=0960-894X&rft.au=JIBLAOUI,%20Ahmad&LEROY-LHEZ,%20Stephanie&OUK,%20Tan-Sothea&GRENIER,%20Karine&SOL,%20Vincent&rft.genre=article


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