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Thermal microscopy of single biological cells

dc.contributor.authorLEGRAND, R.
dc.contributor.authorGHANEM, M. Abi
dc.contributor.authorPLAWINSKI, Laurent
dc.contributor.authorDURRIEU, Marie‐Christine
dc.contributor.authorAUDOIN, B.
dc.contributor.authorDEHOUX, T.
dc.date.accessioned2020-09-03T08:02:03Z
dc.date.available2020-09-03T08:02:03Z
dc.date.issued2015
dc.identifier.issn0003-6951
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/10960
dc.description.abstractEnTechniques that can probe the thermal properties of cells are used in many applications ranging from cryogenic preservation to hyperthermia therapy, and provide powerful tools to investigate diseased conditions. The structural complexity of cells, however, requires innovative modalities operating at a subcell scale. We developed a label-free, non-ionizing technique based on a thermoelastic lens. With this device, we captured images of single cells with a similar to 2 mu m resolution based on thermal properties as the contrast mechanism. To investigate the thermorheological behaviour of cells, we present simultaneous acoustic imaging using an inverted opto-acoustic microscope. Acoustic impedances extracted from the acoustic images support the effusivity obtained from the thermal images. This technique should provide diagnostic tools at the single cell scale. (C) 2015 AIP Publishing LLC.
dc.language.isoen
dc.title.enThermal microscopy of single biological cells
dc.typeArticle de revue
dc.subject.halChimie/Matériaux
bordeaux.journalApplied Physics Letters
bordeaux.page63703-63703
bordeaux.volume107
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN) - UMR 5248*
bordeaux.hal.laboratoriesInstitut de Chimie & de Biologie des Membranes & des Nano-objets (CBMN, UMR 5248)
bordeaux.issue26
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Applied%20Physics%20Letters&rft.date=2015&rft.volume=107&rft.issue=26&rft.spage=63703-63703&rft.epage=63703-63703&rft.eissn=0003-6951&rft.issn=0003-6951&rft.au=LEGRAND,%20R.&GHANEM,%20M.%20Abi&PLAWINSKI,%20Laurent&DURRIEU,%20Marie%E2%80%90Christine&AUDOIN,%20B.&rft.genre=article


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