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Prevalence of atheromatous and non-atheromatous cardiovascular disease by age in chronic kidney disease

hal.structure.identifierHôpital Ambroise Paré [AP-HP]
hal.structure.identifierCentre de recherche en épidémiologie et santé des populations [CESP]
dc.contributor.authorVILLAIN, Cédric
hal.structure.identifierCentre de recherche en épidémiologie et santé des populations [CESP]
dc.contributor.authorMETZGER, Marie
hal.structure.identifierService de Néphrologie-Transplantation-Dialyse
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorCOMBE, Christian
hal.structure.identifierCentre Hospitalier Lyon Sud [CHU - HCL] [CHLS]
dc.contributor.authorFOUQUE, Denis
hal.structure.identifierCentre Hospitalier Régional Universitaire de Nancy [CHRU Nancy]
hal.structure.identifierMaladies chroniques, santé perçue, et processus d'adaptation [APEMAC]
dc.contributor.authorFRIMAT, Luc
hal.structure.identifierAgence de la biomédecine [Saint-Denis la Plaine]
hal.structure.identifierCentre de recherche en épidémiologie et santé des populations [CESP]
dc.contributor.authorJACQUELINET, Christian
hal.structure.identifierCentre Hospitalier Lyon Sud [CHU - HCL] [CHLS]
dc.contributor.authorLAVILLE, Maurice
hal.structure.identifierMaladies chroniques, santé perçue, et processus d'adaptation [APEMAC]
dc.contributor.authorBRIANÇON, Serge
hal.structure.identifierInstitut de médecine moléculaire de Rangueil [I2MR]
hal.structure.identifierUniversité Toulouse III - Paul Sabatier [UT3]
dc.contributor.authorKLEIN, Julie
hal.structure.identifierInstitut de médecine moléculaire de Rangueil [I2MR]
hal.structure.identifierUniversité Toulouse III - Paul Sabatier [UT3]
dc.contributor.authorSCHANSTRA, Joost
hal.structure.identifierArbor Research Collaborative for Health
dc.contributor.authorROBINSON, Bruce
hal.structure.identifierCentre de recherche en épidémiologie et santé des populations [CESP]
dc.contributor.authorMANSENCAL, Nicolas
hal.structure.identifierCentre de recherche en épidémiologie et santé des populations [CESP]
dc.contributor.authorSTENGEL, Bénédicte
hal.structure.identifierService Néphrologie/Dialyse [AP-HP Ambroise-Paré]
hal.structure.identifierCentre de recherche en épidémiologie et santé des populations [CESP]
dc.contributor.authorMASSY, Ziad
dc.contributor.authorHANNEDOUCHE, T
dc.contributor.authorMOULIN, B.
dc.contributor.authorKLEIN, A
dc.contributor.authorBOURDENX, J
dc.contributor.authorKELLER, A
dc.contributor.authorDELCLAUX, C
dc.contributor.authorVENDRELY, B.
dc.contributor.authorDEROURE, B
dc.contributor.authorLACRAZ, A
dc.contributor.authorLOBBEDEZ, T.
dc.contributor.authorLANDRU, I
dc.contributor.authorLANG, P.
dc.contributor.authorBELENFANT, X.
dc.contributor.authorTHERVET, E.
dc.contributor.authorURENA, P
dc.contributor.authorDELAHOUSSE, M
dc.contributor.authorVELA, C
dc.contributor.authorESSIG, M
dc.contributor.authorSEKHRI, H
dc.contributor.authorSMATI, M
dc.contributor.authorJAMALI, M
dc.contributor.authorHACQ, B
dc.contributor.authorPANESCU, V
dc.contributor.authorBELLOU, M
dc.contributor.authorKAMAR, Nassim
dc.contributor.authorNOËL, C.
dc.contributor.authorGLOWACKI, F.
dc.contributor.authorMAISONNEUVE, N
dc.contributor.authorAZAR, R.
dc.contributor.authorHOFFMANN, M
dc.contributor.authorHOURMANT, M.
dc.contributor.authorTESTA, A
dc.contributor.authorBESNIER, D.
dc.contributor.authorCHOUKROUN, Gabriel
dc.contributor.authorLAMBREY, G
dc.contributor.authorBURTEY, Stéphane
dc.contributor.authorLEBRUN, G
dc.contributor.authorMAGNANT, E
dc.contributor.authorJUILLARD, L.
dc.contributor.authorCHAZOT, C
dc.contributor.authorZAOUI, P
dc.contributor.authorKUENTZ, F
dc.date.accessioned2021-06-10T07:04:51Z
dc.date.available2021-06-10T07:04:51Z
dc.date.issued2018-08-28
dc.identifier.issn0931-0509
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/78999
dc.description.abstractEnBackground:Although chronic kidney disease (CKD) and age are major risk factors for cardiovascular disease (CVD), little is known about the relative proportions of atheromatous and non-atheromatous CVD by age in CKD patients.Methods:We used baseline data from the French Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) cohort of 3033 patients (65% men) with CKD Stages 3-4 to study crude and adjusted associations between age, the estimated glomerular filtration rate (eGFR), atheromatous CVD (coronary artery disease, peripheral artery disease and stroke) and non-atheromatous CVD (heart failure, cardiac arrhythmia and valvular heart disease).Results:Mean age was 66.8 and mean Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) eGFR was 32.9 mL/min/1.73 m2. In the <65, (65-74), (75-84) and ≥85 year age groups, the prevalence was, respectively, 18.7, 35.5, 42.9 and 37.8% for atheromatous CVD, and 14.9, 28.4, 38.1 and 56.4% for non-atheromatous CVD. After adjusting for albuminuria, sex and CVD risk factors, the odds ratio (OR) [95% confidence interval (CI)] for (65-74), (75-84) and ≥85 age groups (compared with the <65 group) was, respectively, 1.99 (1.61-2.46), 2.89 (2.30-3.62), 2.72 (1.77-4.18) for atheromatous CVD and 2.07 (1.66-2.58), 3.15 (2.50-3.97), 7.04 (4.67-10.61) for non-atheromatous CVD. Compared with patients with an eGFR ≥30 mL/min/1.73 m2, those with an eGFR <30 mL/min/1.73 m2 had a higher OR for atheromatous CVD [1.21 (1.01-1.44)] and non-atheromatous CVD [1.16 (0.97-1.38)].Conclusions:In this large cohort of CKD patients, both atheromatous and non-atheromatous CVD were highly prevalent and more frequent in older patients. In a given age group, the prevalence of atheromatous and non-atheromatous CVD was similar (except for a greater prevalence of non-atheromatous CVD after 85).
dc.language.isoen
dc.publisherOxford University Press (OUP)
dc.title.enPrevalence of atheromatous and non-atheromatous cardiovascular disease by age in chronic kidney disease
dc.typeArticle de revue
dc.identifier.doi10.1093/ndt/gfy277
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologie
bordeaux.journalNephrology Dialysis Transplantation
bordeaux.page827-836
bordeaux.volume35
bordeaux.hal.laboratoriesBioingénierie Tissulaire (BioTis) - U1026*
bordeaux.issue5
bordeaux.institutionCNRS
bordeaux.institutionINSERM
bordeaux.institutionCHU de Bordeaux
bordeaux.institutionInstitut Bergonié
bordeaux.peerReviewedoui
hal.identifierhal-02381361
hal.version1
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-02381361v1
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