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Patterning of Endothelial Cells and Mesenchymal Stem Cells by Laser-Assisted Bioprinting to Study Cell Migration

hal.structure.identifierBioingénierie tissulaire [BIOTIS]
hal.structure.identifierUniversité de Montréal [UdeM]
dc.contributor.authorBOURGET, Jean-Michel
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorKÉROURÉDAN, Olivia
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorMEDINA, Manuela
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorRÉMY, Murielle
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorTHÉBAUD, Noélie Brunehilde
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorBAREILLE, Reine
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorCHASSANDE, Olivier
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorAMÉDÉE, Joëlle
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorCATROS, Sylvain
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorDEVILLARD, Raphael
dc.date.accessioned2021-06-10T07:03:54Z
dc.date.available2021-06-10T07:03:54Z
dc.date.issued2016
dc.identifier.issn2314-6133
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/78941
dc.description.abstractEnTissue engineering of large organs is currently limited by the lack of potent vascularization in vitro. Tissue-engineered bone grafts can be prevascularized in vitro using endothelial cells (ECs). The microvascular network architecture could be controlled by printing ECs following a specific pattern. Using laser-assisted bioprinting, we investigated the effect of distance between printed cell islets and the influence of coprinted mesenchymal cells on migration. When printed alone, ECs spread out evenly on the collagen hydrogel, regardless of the distance between cell islets. However, when printed in coculture with mesenchymal cells by laser-assisted bioprinting, they remained in the printed area. Therefore, the presence of mesenchymal cell is mandatory in order to create a pattern that will be conserved over time. This work describes an interesting approach to study cell migration that could be reproduced to study the effect of trophic factors.
dc.language.isoen
dc.publisherHindawi Publishing Corporation
dc.title.enPatterning of Endothelial Cells and Mesenchymal Stem Cells by Laser-Assisted Bioprinting to Study Cell Migration
dc.typeArticle de revue
dc.identifier.doi10.1155/2016/3569843
dc.subject.halSciences du Vivant [q-bio]
bordeaux.journalBioMed Research International
bordeaux.page3569843
bordeaux.volume2016
bordeaux.hal.laboratoriesBioingénierie Tissulaire (BioTis) - U1026*
bordeaux.institutionCNRS
bordeaux.institutionINSERM
bordeaux.institutionCHU de Bordeaux
bordeaux.institutionInstitut Bergonié
bordeaux.peerReviewedoui
hal.identifierinserm-02870941
hal.version1
hal.origin.linkhttps://hal.archives-ouvertes.fr//inserm-02870941v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=BioMed%20Research%20International&rft.date=2016&rft.volume=2016&rft.spage=3569843&rft.epage=3569843&rft.eissn=2314-6133&rft.issn=2314-6133&rft.au=BOURGET,%20Jean-Michel&K%C3%89ROUR%C3%89DAN,%20Olivia&MEDINA,%20Manuela&R%C3%89MY,%20Murielle&TH%C3%89BAUD,%20No%C3%A9lie%20Brunehilde&rft.genre=article


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