Prevalence of lung function impairment in cured pulmonary tuberculosis patients in Cotonou, Benin
| dc.rights.license | open | en_US |
| dc.contributor.author | FIOGBE, A. A. | |
| dc.contributor.author | AGODOKPESSI, G. | |
| dc.contributor.author | TESSIER, J. F. | |
| dc.contributor.author | AFFOLABI, D. | |
| dc.contributor.author | ZANNOU, D. M. | |
| dc.contributor.author | ADE, G. | |
| dc.contributor.author | ANAGONOU, S. | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | RAHERISON-SEMJEN, Chantal | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | MARCY, Olivier | |
| dc.date.accessioned | 2020-06-11T07:52:28Z | |
| dc.date.available | 2020-06-11T07:52:28Z | |
| dc.date.issued | 2019-02-01 | |
| dc.identifier.issn | 1027-3719 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/7876 | |
| dc.description.abstractEn | SETTING: National teaching hospital for the management of respiratory diseases, Cotonou, Benin. OBJECTIVE: 1) To estimate the prevalence of lung function impairment (LFI) and associated factors in patients cured of pulmonary tuberculosis (PTB); and 2) to determine the link between human immunodeficiency virus (HIV) infection and LFI occurrence. DESIGN: We performed a cross-sectional study in cured patients with smear-positive TB (PTB+) treated between 2012 and 2015. We recruited two control groups of 70 HIV-infected (HIV+/TB-) and 70 HIV-negative participants without TB (HIV-/TB-). We performed spirometry in all participants to identify LFI (obstructive, restrictive or mixed) and the 6-min walk test (6-MWT) in PTB+ participants. We assessed the factors associated with LFI using logistic regression. RESULTS: Of 4711 subjects with PTB, 241 were contacted and 189 were included. The median age was 37 years; 128 (68.0%) were male. Overall, 85 cured PTB+ patients had LFI (45.0%). Extent of initial radiological lesions, time between symptom onset and treatment, and female sex were independently associated with LFI. Fifty-five (29.1%) cured PTB+ patients had an abnormal 6-MWT; those with LFI had a higher risk of poor exercise tolerance (OR 2.23; interquartile range 1.16-4.30). We did not find any association between HIV infection and LFI. CONCLUSION: LFI is very common in cured PTB+ patients from Benin and significantly impacts exercise tolerance. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | IDLIC | |
| dc.subject.en | FR | |
| dc.subject.en | EPICENE | |
| dc.subject.en | ISPED | |
| dc.title.en | Prevalence of lung function impairment in cured pulmonary tuberculosis patients in Cotonou, Benin | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.5588/ijtld.18.0234 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 30808452 | en_US |
| bordeaux.journal | International Journal of Tuberculosis and Lung Disease | en_US |
| bordeaux.page | 195-202 | en_US |
| bordeaux.volume | 23 | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - U1219 | en_US |
| bordeaux.issue | 2 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.team | EPICENE_BPH | |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-03211430 | |
| hal.version | 1 | |
| hal.date.transferred | 2021-04-28T14:56:33Z | |
| hal.export | true | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=International%20Journal%20of%20Tuberculosis%20and%20Lung%20Disease&rft.date=2019-02-01&rft.volume=23&rft.issue=2&rft.spage=195-202&rft.epage=195-202&rft.eissn=1027-3719&rft.issn=1027-3719&rft.au=FIOGBE,%20A.%20A.&AGODOKPESSI,%20G.&TESSIER,%20J.%20F.&AFFOLABI,%20D.&ZANNOU,%20D.%20M.&rft.genre=article |
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