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Biomechanical evaluation of a bioactive artificial anterior cruciate ligament

hal.structure.identifierInstitut de Mécanique et d'Ingénierie de Bordeaux [I2M]
dc.contributor.authorGUERARD, Sandra
hal.structure.identifierBiomécanique et Pathologie Locomotrice du Cheval [BPLC]
dc.contributor.authorMANASSERO, Mathieu
hal.structure.identifierÉcole nationale vétérinaire d'Alfort [ENVA]
dc.contributor.authorVIATEAU, Véronique
hal.structure.identifierChimie, Structures et Propriétés de Biomatériaux et d'Agents Thérapeutiques [CSPBAT]
dc.contributor.authorMIGONNEY, Véronique
hal.structure.identifierInstitut de Mécanique et d'Ingénierie de Bordeaux [I2M]
dc.contributor.authorSKALLI, Wafa
hal.structure.identifierLaboratoire de Biomécanique et Mécanique des Chocs [LBMC UMR T9406]
dc.contributor.authorMITTON, David
dc.date.accessioned2021-05-14T09:57:03Z
dc.date.available2021-05-14T09:57:03Z
dc.date.issued2014
dc.identifier.issn2287-2094
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/77852
dc.description.abstractEnThis study aimed to assess the biomechanical performance of a new generation of artificial ligament, which can be considered “bioactive” and “biointegrated,” implanted in sheep. Thirty sheep were implanted: 15 sheep received the artificial ligament grafted with a bioactive polymer (grafted) and 15 received the artificial ligament without a bioactive polymer (non-grafted). The animals were sacrificed 3 or 12 months after implantation. The knee kinematics, namely flexion-extension, anterior drawer, and varusvalgus tests, were evaluated using a fully characterized custom-made device. Afterward, the specimens were tested under uniaxial tension until failure.The flexion-extension showed significant differences between (grafted or non-grafted) artificial and native ligaments 3 months after implantation. This difference became non-significant 12 months postoperatively.The anterior tibial drawer was significantly increased 3 months after implantation and remained significantly different only for non-grafted ligament 12 months after implantation.Twelve months after implantation, the differences between grafted and non-grafted ligament biomechanical properties were significant in terms of stiffness. In terms of load to failure, grafted ligaments seem to have had slightly better performance than non-grafted ligaments 12 months postoperatively. Overall these results suggest that grafted artificial ligaments have slightly better biomechanical characteristics than non-grafted artificial ligaments 12 months after implantation in sheep.
dc.language.isoen
dc.publisherTechno-Press
dc.subject.enin vitro experiments
dc.subject.enin vivo integration
dc.subject.enACL reconstruction
dc.subject.enbiomechanics
dc.title.enBiomechanical evaluation of a bioactive artificial anterior cruciate ligament
dc.typeArticle de revue
dc.identifier.doi10.12989/aba.2014.1.4.239
dc.subject.halSciences de l'ingénieur [physics]/Mécanique [physics.med-ph]/Biomécanique [physics.med-ph]
bordeaux.journalAdvances in Biomechanics and Applications
bordeaux.page239-252
bordeaux.volume1
bordeaux.hal.laboratoriesInstitut de Mécanique et d’Ingénierie de Bordeaux (I2M) - UMR 5295*
bordeaux.issue4
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.institutionCNRS
bordeaux.institutionINRAE
bordeaux.institutionArts et Métiers
bordeaux.peerReviewedoui
hal.identifierhal-01164007
hal.version1
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-01164007v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Advances%20in%20Biomechanics%20and%20Applications&rft.date=2014&rft.volume=1&rft.issue=4&rft.spage=239-252&rft.epage=239-252&rft.eissn=2287-2094&rft.issn=2287-2094&rft.au=GUERARD,%20Sandra&MANASSERO,%20Mathieu&VIATEAU,%20V%C3%A9ronique&MIGONNEY,%20V%C3%A9ronique&SKALLI,%20Wafa&rft.genre=article


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