Kinetic Theory Modeling and Efficient Numerical Simulation of Gene Regulatory Networks Based on Qualitative Descriptions
| hal.structure.identifier | Institut de Recherche en Génie Civil et Mécanique [GeM] | |
| dc.contributor.author | CHINESTA, Francisco | |
| hal.structure.identifier | Institut de Recherche en Communications et en Cybernétique de Nantes [IRCCyN] | |
| dc.contributor.author | MAGNIN, Morgan | |
| hal.structure.identifier | Institut de Recherche en Communications et en Cybernétique de Nantes [IRCCyN] | |
| dc.contributor.author | ROUX, Olivier | |
| hal.structure.identifier | Laboratoire Angevin de Mécanique, Procédés et InnovAtion [LAMPA] | |
| dc.contributor.author | AMMAR, Amine | |
| hal.structure.identifier | Aragón Institute of Engineering Research [Zaragoza] [I3A] | |
| dc.contributor.author | CUETO, Elías | |
| dc.date.accessioned | 2021-05-14T09:56:13Z | |
| dc.date.available | 2021-05-14T09:56:13Z | |
| dc.date.issued | 2015-04 | |
| dc.identifier.issn | 1099-4300 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/77758 | |
| dc.description.abstractEn | In this work, we begin by considering the qualitative modeling of biological regulatory systems using process hitting, from which we define its probabilistic counterpart by considering the chemical master equation within a kinetic theory framework. The last equation is efficiently solved by considering a separated representation within the proper generalized decomposition framework that allows circumventing the so-called curse of dimensionality. Finally, model parameters can be added as extra-coordinates in order to obtain a parametric solution of the model. | |
| dc.language.iso | en | |
| dc.publisher | MDPI | |
| dc.subject.en | statistical mechanics | |
| dc.subject.en | kinetic theory | |
| dc.subject.en | chemical master equation | |
| dc.subject.en | proper generalized decomposition (PGD) | |
| dc.subject.en | qualitative modeling | |
| dc.subject.en | process hitting | |
| dc.subject.en | biological regulatory networks | |
| dc.title.en | Kinetic Theory Modeling and Efficient Numerical Simulation of Gene Regulatory Networks Based on Qualitative Descriptions | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.3390/e17041896 | |
| dc.subject.hal | Sciences de l'ingénieur [physics]/Mécanique [physics.med-ph]/Mécanique des fluides [physics.class-ph] | |
| bordeaux.journal | Entropy | |
| bordeaux.page | 1896-1915 | |
| bordeaux.volume | 17 | |
| bordeaux.hal.laboratories | Institut de Mécanique et d’Ingénierie de Bordeaux (I2M) - UMR 5295 | * |
| bordeaux.issue | 4 | |
| bordeaux.institution | Université de Bordeaux | |
| bordeaux.institution | Bordeaux INP | |
| bordeaux.institution | CNRS | |
| bordeaux.institution | INRAE | |
| bordeaux.institution | Arts et Métiers | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-01195963 | |
| hal.version | 1 | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-01195963v1 | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Entropy&rft.date=2015-04&rft.volume=17&rft.issue=4&rft.spage=1896-1915&rft.epage=1896-1915&rft.eissn=1099-4300&rft.issn=1099-4300&rft.au=CHINESTA,%20Francisco&MAGNIN,%20Morgan&ROUX,%20Olivier&AMMAR,%20Amine&CUETO,%20El%C3%ADas&rft.genre=article |
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