Afficher la notice abrégée

Mapping of drug-related problems among older adults conciliating medical and pharmaceutical approaches

dc.rights.licenseopenen_US
dc.contributor.authorLAROCHE, Marie-Laure
dc.contributor.authorVAN NGO, Thi Hong
dc.contributor.authorSIROIS, Caroline
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDAVELUY, Amelie
dc.contributor.authorGUILLAUMIN, Michel
dc.contributor.authorVALNET-RABIER, Marie-Blanche
dc.contributor.authorGRAU, Muriel
dc.contributor.authorROUX, Barbara
dc.contributor.authorMERLE, Louis
dc.date.accessioned2021-05-12T13:34:37Z
dc.date.available2021-05-12T13:34:37Z
dc.date.issued2021-03-20
dc.identifier.issn1878-7649 (Print) 1878-7649en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/74545
dc.description.abstractEnPURPOSE: To lay the fundamentals of drug-related problems (DRPs) in older adults, and to organize them according to a logical process conciliating medical and pharmaceutical approaches, to better identify the causes and consequences of DRPs. MATERIALS AND METHODS: A narrative overview. RESULTS: The causes of DRPs may be intentional or unintentional. They lie in poor prescription, poor adherence, medication errors (MEs) and substance use disorders (SUD). Poor prescription encompasses sub-optimal or off-label drug choice; this choice is either intentional or unintentional, often within a polypharmacy context and not taking sufficiently into account the patient's clinical condition. Poor adherence is often the consequence of a complicated administration schedule. This review shows that MEs are not the most frequent causes of DRPs. SUD are little studied in older adults and needs to be more investigated because the use of psychoactive substances among older people is frequent. Prescribers, pharmacists, nurses, patients, and caregivers all play a role in different causes of DRPs. The potential deleterious outcomes of DRPs result from adverse drug reactions and therapeutic failures. These can lead to a negative benefit-risk ratio for a given treatment regimen. DISCUSSION/CONCLUSION: Interdisciplinary pharmacotherapy programs show significant clinical impacts in preventing or resolving adverse drug events and, suboptimal responses. New technologies also seem to be interesting solutions to prevent MEs. Better communication between healthcare professionals, patients and their caregivers would ensure greater safety and effectiveness of treatments.
dc.language.isoENen_US
dc.subject.enDrug-related problems
dc.subject.enOlder adults
dc.subject.enCompliance
dc.subject.enMedication error
dc.subject.enPrescription
dc.subject.enSubstance use disorders
dc.title.enMapping of drug-related problems among older adults conciliating medical and pharmaceutical approaches
dc.typeArticle de revueen_US
dc.identifier.doi10.1007/s41999-021-00482-8en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed33745106en_US
bordeaux.journalEuropean Geriatric Medicineen_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamPharmacoEpi-Drugsen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03225474
hal.version1
hal.date.transferred2021-05-12T13:34:41Z
hal.exporttrue
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=European%20Geriatric%20Medicine&rft.date=2021-03-20&rft.eissn=1878-7649%20(Print)%201878-7649&rft.issn=1878-7649%20(Print)%201878-7649&rft.au=LAROCHE,%20Marie-Laure&VAN%20NGO,%20Thi%20Hong&SIROIS,%20Caroline&DAVELUY,%20Amelie&GUILLAUMIN,%20Michel&rft.genre=article


Fichier(s) constituant ce document

FichiersTailleFormatVue

Il n'y a pas de fichiers associés à ce document.

Ce document figure dans la(les) collection(s) suivante(s)

Afficher la notice abrégée