The role of ultra-sensitive molecular methods for detecting malaria - the broader perspective
| dc.rights.license | open | en_US |
| dc.contributor.author | KAMALIDDIN, Claire | |
| dc.contributor.author | SUTHERLAND, Colin J. | |
| dc.contributor.author | HOUZE, Sandrine | |
| dc.contributor.author | COTTRELL, Gilles | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | BRIAND, Valerie | |
| dc.contributor.author | MOGOLLON, Daniel Castaneda | |
| dc.contributor.author | PILLAI, Dylan R. | |
| dc.date.accessioned | 2021-05-10T09:24:28Z | |
| dc.date.available | 2021-05-10T09:24:28Z | |
| dc.date.issued | 2021-03-09 | |
| dc.identifier.issn | 1537-6591 (Electronic) 1058-4838 (Linking) | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/27224 | |
| dc.description.abstractEn | Ultra-sensitive molecular diagnostics are lowering the limit of detection for malaria parasites in the blood and providing insights not captured by conventional tool such as microscopy and rapid antigen tests. Low-level malaria infections identified by molecular tools may influence clinical outcomes, transmission events, and elimination efforts. While many ultra-sensitive molecular methods require well-equipped laboratories, technologies such as loop-mediated isothermal amplification (LAMP) or recombinase polymerase amplification (RPA) provide more portable and analytically sensitive solutions. These tools may benefit asymptomatic patient screening, antenatal care, and elimination campaigns. We review the recent evidence, offer our perspective on the impact of these new tests and identify future research priorities. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | Malaria | |
| dc.subject.en | Molecular | |
| dc.subject.en | Diagnostics | |
| dc.subject.en | PCR | |
| dc.subject.en | LAMP | |
| dc.title.en | The role of ultra-sensitive molecular methods for detecting malaria - the broader perspective | |
| dc.title.alternative | Clin Infect Dis | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1093/cid/ciab221 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 33693719 | en_US |
| bordeaux.journal | Clinical Infectious Diseases | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | IDLIC | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-03222390 | |
| hal.version | 1 | |
| hal.date.transferred | 2021-05-10T09:24:32Z | |
| hal.export | true | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Clinical%20Infectious%20Diseases&rft.date=2021-03-09&rft.eissn=1537-6591%20(Electronic)%201058-4838%20(Linking)&rft.issn=1537-6591%20(Electronic)%201058-4838%20(Linking)&rft.au=KAMALIDDIN,%20Claire&SUTHERLAND,%20Colin%20J.&HOUZE,%20Sandrine&COTTRELL,%20Gilles&BRIAND,%20Valerie&rft.genre=article |
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