Nasal high-frequency percussive ventilation vs nasal continuous positive airway pressure in newborn infants respiratory distress: A cross over clinical trial
| dc.rights.license | open | en_US |
| dc.contributor.author | RENESME, L. | |
| dc.contributor.author | DUMAS DE LA ROQUE, E. | |
| dc.contributor.author | GERMAIN, C. | |
| dc.contributor.author | CHEVRIER, A. | |
| dc.contributor.author | REBOLA, M. | |
| dc.contributor.author | CRAMAREGEAS, S. | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | BENARD, Antoine | |
| dc.contributor.author | ELLEAU, C. | |
| dc.contributor.author | TANDONNET, O. | |
| dc.date.accessioned | 2021-03-18T08:28:51Z | |
| dc.date.available | 2021-03-18T08:28:51Z | |
| dc.date.issued | 2020-10 | |
| dc.identifier.issn | 1099-0496 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/26713 | |
| dc.description.abstractEn | OBJECTIVE: To determine if nasal high-frequency percussive ventilation (nHFPV) to manage neonatal respiratory distress decreases the regional cerebral oxygen saturation (rScO(2) ) compared to nasal CPAP. STUDY DESIGN: A prospective, randomized, monocentric, open-label, non-inferiority crossover trial. Newborns of gestational age (GA) ≥ 33 weeks exhibiting persistent respiratory distress after 10 min of life were treated with nHFPV and nCPAP, in succession and in random order. The primary endpoint was the mean rScO(2) , as revealed by near-infrared spectroscopy (NIRS). RESULTS: Forty-nine newborns were randomized; the mean GA and birth weight were 36.4 ± 1.9 weeks and 2,718 ± 497 g. The mean rScO(2) difference during the last 5 min of each ventilation mode (nHFPV minus nCPAP) was -0.7 ± 5.4% (95% CI -2.25; 0.95%). CONCLUSION: In our study on newborns of GA ≥ 33 weeks treated for respiratory distress, cerebral oxygenation via nHFPV was not inferior to nCPAP. This article is protected by copyright. All rights reserved. | |
| dc.language.iso | EN | en_US |
| dc.title.en | Nasal high-frequency percussive ventilation vs nasal continuous positive airway pressure in newborn infants respiratory distress: A cross over clinical trial | |
| dc.title.alternative | Pediatr Pulmonol | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1002/ppul.24935 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 32609946 | en_US |
| bordeaux.journal | Pediatric Pulmonology | en_US |
| bordeaux.page | 2617-2623 | en_US |
| bordeaux.volume | 55 | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.issue | 10 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.team | PharmacoEpi-Drugs | en_US |
| bordeaux.team | EMOS | en_US |
| bordeaux.team | USMR | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-03172879 | |
| hal.version | 1 | |
| hal.date.transferred | 2021-03-18T08:28:54Z | |
| hal.export | true | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Pediatric%20Pulmonology&rft.date=2020-10&rft.volume=55&rft.issue=10&rft.spage=2617-2623&rft.epage=2617-2623&rft.eissn=1099-0496&rft.issn=1099-0496&rft.au=RENESME,%20L.&DUMAS%20DE%20LA%20ROQUE,%20E.&GERMAIN,%20C.&CHEVRIER,%20A.&REBOLA,%20M.&rft.genre=article |
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