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Association between cellular HIV-1 DNA level and mortality in HIV-1 infected African adults starting ART with high CD4 counts

dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorN'TAKPE, Jean-Baptiste
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorGABILLARD, Delphine
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorMOH, Desmorys Raoul
dc.contributor.authorGARDIENNET, E.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorEMIEME, Arlette
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorBADJE, Anani Dodzi
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorKOUAME, Menan Gerard
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorTONI, Thomas-D'Aquin
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorKARCHER, Sophie
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorLE CARROU, Jérôme
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorMENAN, Herve
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDANEL, Christine
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorEHOLIE, Serge Paul
dc.contributor.authorROUZIOUX, C.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorANGLARET, Xavier
dc.date.accessioned2021-02-08T15:46:42Z
dc.date.available2021-02-08T15:46:42Z
dc.date.issued2020
dc.identifier.issn2352-3964en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/26183
dc.description.abstractEnBackground High HIV-1 DNA levels in peripheral blood mononuclear cells (PBMC) were associated with a higher risk of severe morbidity and a faster decline in CD4 count in ART-naive patients. We report the association between HIV-1 DNA and mortality in HIV-infected adults in a trial of early ART in West Africa. Methods In the Temprano trial, HIV-infected adults were randomly assigned to start ART immediately or defer ART. After trial termination, HIV-1 DNA was measured in whole blood samples frozen at baseline. We analyzed the association between baseline PBMC HIV-1 DNA and long-term mortality.
dc.language.isoENen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subjectIDLIC
dc.title.enAssociation between cellular HIV-1 DNA level and mortality in HIV-1 infected African adults starting ART with high CD4 counts
dc.title.alternativeEBioMedicineen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.ebiom.2020.102815en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
bordeaux.journalEBioMedicineen_US
bordeaux.page102815en_US
bordeaux.volume56en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - U1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.teamIDLICen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03135051
hal.version1
hal.date.transferred2021-02-08T15:46:48Z
hal.exporttrue
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