Effect of poor glycemic control in cognitive performance in the elderly with type 2 diabetes mellitus: The Mexican Health and Aging Study
| dc.rights.license | open | en_US |
| dc.contributor.author | MIMENZA-ALVARADO, A. J. | |
| dc.contributor.author | JIMENEZ-CASTILLO, G. A. | |
| dc.contributor.author | YEVERINO-CASTRO, S. G. | |
| dc.contributor.author | BARRAGAN-BERLANGA, A. J. | |
| dc.contributor.author | PEREZ-ZEPEDA, M. U. | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | AVILA-FUNES, Jose Alberto | |
| dc.contributor.author | AGUILAR-NAVARRO, S. G. | |
| dc.date.accessioned | 2021-02-05T09:51:30Z | |
| dc.date.available | 2021-02-05T09:51:30Z | |
| dc.date.issued | 2020 | |
| dc.identifier.issn | 1471-2318 (Electronic) 1471-2318 (Linking) | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/26146 | |
| dc.description.abstractEn | Background Cognitive impairment is twice more frequent in elderly with type 2 diabetes mellitus (DM). This study was conducted to determine the association between glycemic control and cognitive performance among community-dwelling elderly persons in Mexico. Methods Cross-sectional study conducted in individuals aged 60 years or elderly participating in the 2012 Mexican Health and Aging Study. Type 2 DM participants were classified in 3 groups according to their glycated hemoglobin levels (HbA1c): < 7% (intensive control), 7–7.9% (standard control) or ≥ 8% (poor control), and cognitive performance: low (CCCE ≤44 points), intermediate (44.1–59.52 points), or high (≥59.53 points). Multinomial logistic regression models were constructed to determine this association. Results Two hundred sixteen community-dwelling adults aged 60 and older with type 2 diabetes were selected. Subjects in the low cognitive performance group were older (69.7 ± 6.6 vs 65.86 ± 5.18 years, p < .001) and had a lower educational level (2.5 ± 2.6 vs 7.44 ± 4.15 years, p < .000) when compared to the high cognitive performance participants. HbA1c ≥ 8% was associated with having low (Odds Ratio (OR) 3.17, 95% CI 1.17–8.60, p = .024), and intermediate (OR 3.23, 95% CI 1.27–8.20, p = .014) cognitive performance; this trend was not found for HbA1c 7.0–7.9% group. The multinomial regression analysis showed that the presence of HbA1c ≥ 8% (poor glycemic control) was associated with low (OR 3.17, 95% CI = 1.17–8.60, p = .024), and intermediate (OR 3.23, 95% CI = 1.27–8.20, p = .014) cognitive performance. After adjusting for confounding variables. Conclusions Glycemic control with a HbA1c ≥ 8% was associated with worse cognitive performance. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
| dc.subject | SEPIA | |
| dc.title.en | Effect of poor glycemic control in cognitive performance in the elderly with type 2 diabetes mellitus: The Mexican Health and Aging Study | |
| dc.title.alternative | BMC Geriatr | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1186/s12877-020-01827-x | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 33096995 | en_US |
| bordeaux.journal | BMC Geriatrics | en_US |
| bordeaux.page | 424 | en_US |
| bordeaux.volume | 20 | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.issue | 1 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.team | SEPIA | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-03132503 | |
| hal.version | 1 | |
| hal.date.transferred | 2021-02-05T09:51:34Z | |
| hal.export | true | |
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